Anxiety and mortality risk in community-dwelling elderly people

Isabelle Carriere, Joanne Ryan, Joanna Norton, Jacqueline Scali, Robert Stewart, Karen Ritchie, Marie-Laure Ancelin

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26 Citations (Scopus)


Background: There are conflicting data on the role of anxiety in predicting mortality. Aims: To evaluate the 10-year mortality risk associated with anxiety in community-dwelling elderly people. Method Using data from 718 men and 1046 women aged 65 years and over, gender-stratified associations of anxiety symptoms (Spielberger State-Trait Anxiety Inventory, third tertile) and current DSM-IV anxiety disorder including generalised anxiety disorder (GAD) and phobia with all-cause and cardiovascular mortality were determined. Results: In women, mortality risk was increased for anxiety disorder and GAD in multivariate Cox models (hazard ratio (HR) = 1.53, 95% CI 1.02-2.27 and HR = 2.04, 95% CI 1.08-86 respectively), whereas for phobia it was nearly significant (HR = 1.52, 95% CI 0.94-2.47). Anxiety trait symptoms became non-significant as a result of the confounding effect of depressive symptoms. Anxiety disorder was associated with cardiovascular mortality in univariate analysis (HR = 2.42, 95% CI 1.16-5.07). No significant associations were found in men. Conclusions: Our study suggests a gender-specific association of anxiety and mortality.

Original languageEnglish
Pages (from-to)303-309
Number of pages7
JournalBritish Journal of Psychiatry
Issue number4
Publication statusPublished - Oct 2013
Externally publishedYes

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