Abstract
The induction of an antiviral response in cultured Aedes aegypti cells was compared with that in duck embryo fibroblasts using 32P-labeled double-stranded RNA (dsRNA) from reovirus and poly(rI-rC). Although A. aegypti cells could incorporate a comparable amount of dsRNA (80%), no antiviral response was observed. Further studies using poly(rI-rC) under conditions shown to be optimal for vertebrate cells failed to give positive results. An attempt in Bombyx mori larvae to measure a cellular response to foreign material (a coliphage) injected into the hemocoel resulted in the persistence of the virus for at least 8 days.
| Original language | English |
|---|---|
| Pages (from-to) | 44-49 |
| Number of pages | 6 |
| Journal | Journal of Invertebrate Pathology |
| Volume | 29 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - Jan 1977 |
| Externally published | Yes |
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