Antiplatelet therapy: present status and future prospects

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Abstract

The excessive accumulation of platelets at sites of vascular injury is a key event in the development of arterial thrombosis, the principal pathogenic mechanism underlying the acute coronary syndromes and ischaemic stroke. In combination, these disorders are the leading causes of morbidity and mortality in the industrialised world and, as a consequence, the platelet is a major therapeutic target in the management of cardiovascular disease. This perspective focuses on the present state of antiplatelet therapy and potential future strategies to improve the safety and efficacy of antiplatelet agents.
Original languageEnglish
Pages (from-to)1035 - 1040
Number of pages6
JournalExpert Opinion on Drug Discovery
Volume2
Issue number8
Publication statusPublished - 2007

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