Antioxidants and other pharmacological treatments for Friedreich ataxia (Review)

Mary Kearney, Richard Orrell, Michael Fahey, Massimo Pandolfo

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)


Friedreich ataxia is a rare inherited autosomal recessive neurological disorder, characterised initially by unsteadiness in standing and walking, slowly progressing to wheelchair dependency usually in the late teens or early twenties. It is associated with slurred speech, scoliosis and pes cavus. Heart abnormalities cause premature death in 60 to 80 of people with the disorder. There is no easily defined clinical or biochemical marker and no known treatment. This is the first update of a review published in 2009.
Original languageEnglish
Article numberCD007791
Number of pages26
JournalCochrane Database of Systematic Reviews
Issue number4
Publication statusPublished - 2012

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