Antioxidants and other pharmacological treatments for Friedreich ataxia (Review)

Mary Kearney; Richard W Orrell; Michael Collingwood Fahey; Massimo Pandolfo

doi:10.1002/14651858.CD007791.pub2

Antioxidants and other pharmacological treatments for Friedreich ataxia (Review)

Mary Kearney, Richard W Orrell, Michael Collingwood Fahey, Massimo Pandolfo

Paediatrics Monash Health

Research output: Contribution to journal › Article › Research › peer-review

54 Citations (Scopus)

Abstract

Friedreich ataxia is a rare inherited, autosomal recessive, neurological disorder characterised initially by unsteadiness in standing and walking, slowly progressing to wheelchair dependency usually in the late teens or early twenties. It is associated with slurred speech, scoliosis, pes cavus and heart abnormalities which may cause premature death in 60 to 80 of people. There is no easily defined clinical or biochemical marker and no known treatment.

Original language	English
Article number	CD007791
Number of pages	23
Journal	Cochrane Database of Systematic Reviews
Volume	2009
Issue number	4
DOIs	https://doi.org/10.1002/14651858.CD007791.pub2
Publication status	Published - 2009

Access to Document

10.1002/14651858.CD007791.pub2

Cite this

@article{c9c412093d00491291a21d2645c9d539,

title = "Antioxidants and other pharmacological treatments for Friedreich ataxia (Review)",

abstract = "Friedreich ataxia is a rare inherited, autosomal recessive, neurological disorder characterised initially by unsteadiness in standing and walking, slowly progressing to wheelchair dependency usually in the late teens or early twenties. It is associated with slurred speech, scoliosis, pes cavus and heart abnormalities which may cause premature death in 60 to 80 of people. There is no easily defined clinical or biochemical marker and no known treatment.",

author = "Mary Kearney and Orrell, {Richard W} and Fahey, {Michael Collingwood} and Massimo Pandolfo",

year = "2009",

doi = "10.1002/14651858.CD007791.pub2",

language = "English",

volume = "2009",

journal = "Cochrane Database of Systematic Reviews",

issn = "1469-493X",

publisher = "John Wiley & Sons",

number = "4",

}

TY - JOUR

T1 - Antioxidants and other pharmacological treatments for Friedreich ataxia (Review)

AU - Kearney, Mary

AU - Orrell, Richard W

AU - Fahey, Michael Collingwood

AU - Pandolfo, Massimo

PY - 2009

Y1 - 2009

N2 - Friedreich ataxia is a rare inherited, autosomal recessive, neurological disorder characterised initially by unsteadiness in standing and walking, slowly progressing to wheelchair dependency usually in the late teens or early twenties. It is associated with slurred speech, scoliosis, pes cavus and heart abnormalities which may cause premature death in 60 to 80 of people. There is no easily defined clinical or biochemical marker and no known treatment.

AB - Friedreich ataxia is a rare inherited, autosomal recessive, neurological disorder characterised initially by unsteadiness in standing and walking, slowly progressing to wheelchair dependency usually in the late teens or early twenties. It is associated with slurred speech, scoliosis, pes cavus and heart abnormalities which may cause premature death in 60 to 80 of people. There is no easily defined clinical or biochemical marker and no known treatment.

UR - http://www.mrw.interscience.wiley.com/cochrane/clsysrev/articles/CD007791/frame.html

U2 - 10.1002/14651858.CD007791.pub2

DO - 10.1002/14651858.CD007791.pub2

M3 - Article

SN - 1469-493X

VL - 2009

JO - Cochrane Database of Systematic Reviews

JF - Cochrane Database of Systematic Reviews

IS - 4

M1 - CD007791

ER -

Antioxidants and other pharmacological treatments for Friedreich ataxia (Review)

Abstract

Access to Document

Other files and links

Pharmacological treatments for Friedreich ataxia (Review)

Antioxidants and other pharmacological treatments for Friedreich ataxia (Review)

Cite this