Antioxidants and other pharmacological treatments for Friedreich ataxia (Review)

Mary Kearney, Richard W Orrell, Michael Collingwood Fahey, Massimo Pandolfo

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)

Abstract

Friedreich ataxia is a rare inherited, autosomal recessive, neurological disorder characterised initially by unsteadiness in standing and walking, slowly progressing to wheelchair dependency usually in the late teens or early twenties. It is associated with slurred speech, scoliosis, pes cavus and heart abnormalities which may cause premature death in 60 to 80 of people. There is no easily defined clinical or biochemical marker and no known treatment.
Original languageEnglish
Article numberCD007791
Number of pages23
JournalCochrane Database of Systematic Reviews
Volume2009
Issue number4
DOIs
Publication statusPublished - 2009

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