Projects per year
Objective: High quality diets, characterized by nutrient-rich foods, are one of the foundations for health and well-being. Indicators of diet quality, antioxidants, are associated with protection against cardio-metabolic diseases. This study explores relationships between plasma antioxidants and cardio-metabolic risk among Aboriginal people in Australia. Design: As part of a community-driven health promotion programme, we conducted a cross-sectional study including a health-behaviour questionnaire, plasma antioxidants and cardio-metabolic risk markers (anthropometric-, blood pressure measurements, fasting glucose, glycated haemoglobin, lipids, C-reactive protein and albumin-creatinine-ratio) continuous and categorized into population-specific cut-offs. Antioxidants (β-carotene, β-cryptoxanthin, lycopene, lutein-zeaxanthin, retinol and alpha-tocopherol measured using HPLC) were applied to a principal component analysis, which aggregated these into a single component. Linear regression models were applied to investigate associations between the antioxidant component and cardio-metabolic risk markers. Setting: Community in a remote area in Northern Territory, Australia. Participants: A total of 324 Aboriginal people, mean age 35.5 [range 15-75] years. Results: Antioxidant component levels were higher among those with higher self-reported vegetable intake (p<0.01), higher among those with higher self-reported fruit intake (p=0.05) and lower among current smokers (p=0.06). Linear regression revealed an inverse association between the antioxidant component and C-reactive protein (β= -0.01, p<0.01) after adjusting for confounders. Conclusion: Higher plasma antioxidant levels, indicators of diet quality were associated with lower levels of high-sensitivity C-reactive protein in this Aboriginal population in remote Australia. This association suggests plasma antioxidants may be protective against inflammation; however, longitudinal studies are needed to examine this potentially protective relationship.
|Number of pages||12|
|Journal||Public Health Nutrition|
|Publication status||Published - Oct 2021|
- cardio-metabolic risk
- Indigenous people
- Key words:
- Plasma antioxidants
- quality of diet
- 1 Finished
Community-based Interventions to Reduce the Risk of Diabetes and Cardiovascular Disease in Indigenous Australians (gms Id 000401)
O'Dea, K., Daniel, M., Lee, D., McDermott, R., Rowley, K. & Simmons, D.
National Health and Medical Research Council (NHMRC) (Australia)
1/01/00 → 31/12/04