Antimicrobial photodynamic action on dentin using a light-emitting diode light source

Jucaira Giusti, Lourdes Santos-Pinto, Antonio Pizzolito, Kristian Helmerson, Eurico Carvalho-Filho, Christina Kurachi, Vanderlei Bagnato

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75 Citations (Scopus)


Objective: The aim of this study was the evaluation of two different photosensitizers activated by red light emitted by light-emitting diodes (LEDs) in the decontamination of carious bovine dentin. Materials and Methods: Fifteen bovine incisors were used to obtain dentin samples which were immersed in brain-heart infusion culture medium supplemented with 1 glucose, 2 sucrose, and 1 young primary culture of Lactobacillus acidophilus 108 CFU/mL and Streptococcus mutans 108 CFU/mL for caries induction. Three different concentrations of the Photogem solution, a hematoporphyrin derivative (1, 2, and 3 mg/mL) and two different concentrations of toluidine blue O (TBO), a basic dye (0.025 and 0.1 mg/mL) were used.
Original languageEnglish
Pages (from-to)281 - 287
Number of pages7
JournalPhotomedicine and Laser Surgery
Issue number4
Publication statusPublished - 2008
Externally publishedYes

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