Antimalarial Pyrido[1,2-a]benzimidazoles

Albert Ndakala, Richard Gessner, Patricia Gitari, Natasha October, Karen White, Alan Hudson, Foluke Fakorede, David Shackleford, Marcel Kaiser, Clive Yates, Susan Charman, Kelly Chibale

Research output: Contribution to journalArticleResearchpeer-review

74 Citations (Scopus)

Abstract

Malaria continues to take an enormous toll on human health, particularly in tropical regions. The drugs used to treat this disease are far from ideal, and many of these were introduced decades ago. The utility of these medicaments in resource-poor settings is limited by a number of factors, such as high cost, poor compliance, drug resistance, low efficacy, and poor safety.
Original languageEnglish
Pages (from-to)4581 - 4589
Number of pages9
JournalJournal of Medicinal Chemistry
Volume54
DOIs
Publication statusPublished - 2011

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