Antigen presentation in immunity to murine malaria

Research output: Contribution to journalReview ArticleResearchpeer-review

7 Citations (Scopus)

Abstract

Understanding the initiation of cellular immune responses during blood-stage malaria infection is essential for the development of an effective vaccine that improves upon the naturally acquired immune response and induces rapid and long-lasting protection against disease. Recent studies have identified the dendritic cell (DC) subtypes responsible for priming Plasmodium-specific T cells that mediate protection and/or pathology during blood-stage infection. Significant progress has also been made towards understanding DC recognition of Plasmodium parasites through engagement of TLR signalling pathways, as well as the potential for non-TLR ligands to mediate Plasmodium-induced suppression of DC antigen presentation.

Original languageEnglish
Pages (from-to)119-123
Number of pages5
JournalCurrent Opinion in Immunology
Volume23
Issue number1
DOIs
Publication statusPublished - Feb 2011
Externally publishedYes

Cite this

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Antigen presentation in immunity to murine malaria. / Lundie, Rachel J.

In: Current Opinion in Immunology, Vol. 23, No. 1, 02.2011, p. 119-123.

Research output: Contribution to journalReview ArticleResearchpeer-review

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