Antidepressants in the treatment for chronic low back pain: questioning the validity of meta-analyses

Owen Douglas Williamson, Doron Sagman, Robert Bruins, Luc J Boulay, Alexander Schacht

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)


Due to the diversity of previous studies and the pooling methods used, the conclusions regarding the analgesic effect of antidepressants in CLBP drawn from systematic reviews must be interpreted with caution. Appropriately designed and powered studies similar to recently published duloxetine studies are recommended to demonstrate the analgesic effect of antidepressants.
Original languageEnglish
Pages (from-to)E33 - E41
Number of pages9
JournalPain Practice
Issue number2
Publication statusPublished - 2014

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