Antidepressants in stream ecosystems: influence of selective serotonin reuptake inhibitors (SSRIs) on algal production and insect emergence

Erinn K. Richmond, Emma J. Rosi-Marshall, Sylvia S. Lee, Ross M. Thompson, Michael R. Grace

Research output: Contribution to journalArticleResearchpeer-review

Abstract

The effects of pharmaceuticals on aquatic ecosystems are the subject of increasing environmental concern. Of particular interest are a suite of drugs known as selective serotonin reuptake inhibitors (SSRIs), commonly prescribed to treat depression. SSRIs are now detected in the environment worldwide, but their effects on ecosystems are not well understood. We conducted replicated experiments testing for an ecosystem effect of SSRIs in streams. We used artificial stream mesocosms to expose natural biofilms and aquatic insect communities to concentrations (20 μg/L) of fluoxetine or citalopram or a mix of both (totaling 40 μg/L). These concentrations are the lowest found to have an effect on aquatic invertebrates in other studies. Treatments suppressed gross primary production by 29% and community respiration by >43% on rock biofilms but did not affect algal biomass or whole-stream metabolism. A common group of dipteran midges emerged earlier in all SSRI treated streams compared with the controls. Total biomass of emerged adults at day 14 was greater in the SSRI-exposed streams, suggesting that fluoxetine and citalopram may influence developmental processes in some stream insects. Ecosystem function and invertebrate population dynamics are sensitive to pharmaceuticals. Our study demonstrates that chronic exposure to fluoxetine and citalopram has the potential to affect aquatic biota and ecosystem function.

Original languageEnglish
Pages (from-to)845-855
Number of pages11
JournalFreshwater Science
Volume35
Issue number3
DOIs
Publication statusPublished - 1 Sep 2016

Keywords

  • Aquatic insects
  • Ecosystem function
  • Emergence
  • Pharmaceuticals
  • SSRIs

Cite this

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title = "Antidepressants in stream ecosystems: influence of selective serotonin reuptake inhibitors (SSRIs) on algal production and insect emergence",
abstract = "The effects of pharmaceuticals on aquatic ecosystems are the subject of increasing environmental concern. Of particular interest are a suite of drugs known as selective serotonin reuptake inhibitors (SSRIs), commonly prescribed to treat depression. SSRIs are now detected in the environment worldwide, but their effects on ecosystems are not well understood. We conducted replicated experiments testing for an ecosystem effect of SSRIs in streams. We used artificial stream mesocosms to expose natural biofilms and aquatic insect communities to concentrations (20 μg/L) of fluoxetine or citalopram or a mix of both (totaling 40 μg/L). These concentrations are the lowest found to have an effect on aquatic invertebrates in other studies. Treatments suppressed gross primary production by 29{\%} and community respiration by >43{\%} on rock biofilms but did not affect algal biomass or whole-stream metabolism. A common group of dipteran midges emerged earlier in all SSRI treated streams compared with the controls. Total biomass of emerged adults at day 14 was greater in the SSRI-exposed streams, suggesting that fluoxetine and citalopram may influence developmental processes in some stream insects. Ecosystem function and invertebrate population dynamics are sensitive to pharmaceuticals. Our study demonstrates that chronic exposure to fluoxetine and citalopram has the potential to affect aquatic biota and ecosystem function.",
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Antidepressants in stream ecosystems : influence of selective serotonin reuptake inhibitors (SSRIs) on algal production and insect emergence. / Richmond, Erinn K.; Rosi-Marshall, Emma J.; Lee, Sylvia S.; Thompson, Ross M.; Grace, Michael R.

In: Freshwater Science, Vol. 35, No. 3, 01.09.2016, p. 845-855.

Research output: Contribution to journalArticleResearchpeer-review

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T2 - influence of selective serotonin reuptake inhibitors (SSRIs) on algal production and insect emergence

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AU - Rosi-Marshall, Emma J.

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