Anticoagulant regimes in acute continuous hemodiafiltration: A comparative study

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Abstract

OBJECTIVE: To compare and contrast different heparin regimens for extracorporeal circuit anticoagulation in patients receiving acute continuous hemodiafiltration (ACHD). DESIGN: Prospective controlled randomized comparisons of the following regimens: 1) Low dose (500 IU/h) pre-filter heparin versus regional anticoagulation in patients on continuous arteriovenous hemodiafiltration (CAVHD) via A-V shunt. 2) Low dose pre-filter heparin versus no anticoagulation in patients receiving CAVHD via femoral cannulae. 3) Low dose pre-filter heparin versus regional anticoagulation in patients on continuous veno-venous hemodiafiltration (CVVHD). 4) An assessment of the consequences of the use of no anticoagulant in patients predicted to be at high risk of hemorrhagic complications on treatment with CVVHD.
Original languageEnglish
Pages (from-to)329 - 332
Number of pages4
JournalIntensive Care Medicine
Volume19
Issue number6
DOIs
Publication statusPublished - 1993

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