TY - JOUR
T1 - Antibiotic resistance, virulence factors and genetics of clostridium sordellii
AU - Vidor, Callum
AU - Awad, Milena M
AU - Lyras, Dena
PY - 2015
Y1 - 2015
N2 - Clostridium sordellii is gram positive bacterial pathogen of humans and animals. While the incidence of human-related C. sordellii infection is low, the mortality rate associated with infection is high. Of particular concern are C. sordellii infections after child-birth or medical abortion, which have an almost 100 mortality rate. Recent genetic and epidemiological work has increased our understanding of how this pathogen has evolved and how it causes disease. This review will summarise studies involving the genetics of C. sordellii, including an antibiotic resistance profile, the genetic determinants of virulence and mutagenesis of C. sordellii.
AB - Clostridium sordellii is gram positive bacterial pathogen of humans and animals. While the incidence of human-related C. sordellii infection is low, the mortality rate associated with infection is high. Of particular concern are C. sordellii infections after child-birth or medical abortion, which have an almost 100 mortality rate. Recent genetic and epidemiological work has increased our understanding of how this pathogen has evolved and how it causes disease. This review will summarise studies involving the genetics of C. sordellii, including an antibiotic resistance profile, the genetic determinants of virulence and mutagenesis of C. sordellii.
UR - http://www.sciencedirect.com/science/article/pii/S0923250814001831#
U2 - 10.1016/j.resmic.2014.09.003
DO - 10.1016/j.resmic.2014.09.003
M3 - Article
VL - 166
SP - 368
EP - 374
JO - Research in Microbiology
JF - Research in Microbiology
SN - 0923-2508
IS - 4
ER -