Antibiotic resistance: evolution and alternatives

Dinesh Bhandari, Pratigya Thapa, Kabi Thapa, Sarmila Tandukar, Jeevan Bahadur Sherchand

Research output: Contribution to journalArticleOther


Globally, infection control has been challenged by the rapid advent and dissemination of antibiotic resistant microorganisms. The 70-odd years’ history of post antibiotic era has shown that despite the fitness cost, microorganisms will continue to evolve and we now face a never-ending battle of bacterial resistance against the antibiotics of last resort that we have at our disposal. In this article, we give a brief overview of the discovery of antibiotics, the emergence of antibiotic resistance, and the alternative strategies that can be sought for the treatment of infections caused by multidrug resistant bacteria.
Original languageEnglish
Pages (from-to)149-155
Number of pages7
JournalCanadian Journal of Infection Control
Issue number3
Publication statusPublished - 2016
Externally publishedYes

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