Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse

Phyllis Chew, Derek Yuen, Nada Stefanovic, Josefa Pete, Melinda T Coughlan, Karin Jandeleit-Dahm, Merlin Thomas, Franklin Rosenfeldt, Mark Cooper, Judy Bettina De Haan

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71 Citations (Scopus)

Abstract

To investigate the effect of the GPx1-mimetic ebselen on diabetes-associated atherosclerosis and renal injury in a model of increased oxidative stress.
Original languageEnglish
Pages (from-to)3198-3207
Number of pages10
JournalDiabetes
Volume59
Issue number12
DOIs
Publication statusPublished - 2010

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