Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse

Phyllis Chew, Derek Yuen, Nada Stefanovic, Josefa Pete, Melinda T Coughlan, Karin Jandeleit-Dahm, Merlin Thomas, Franklin Rosenfeldt, Mark Cooper, Judy Bettina De Haan

Surgery Alfred Hospital

Research output: Contribution to journal › Article › Research › peer-review

111 Citations (Scopus)

Abstract

To investigate the effect of the GPx1-mimetic ebselen on diabetes-associated atherosclerosis and renal injury in a model of increased oxidative stress.

Original language	English
Pages (from-to)	3198-3207
Number of pages	10
Journal	Diabetes
Volume	59
Issue number	12
DOIs	https://doi.org/10.2337/db10-0195
Publication status	Published - 2010

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10.2337/db10-0195

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Cite this

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title = "Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse",

abstract = "To investigate the effect of the GPx1-mimetic ebselen on diabetes-associated atherosclerosis and renal injury in a model of increased oxidative stress.",

author = "Phyllis Chew and Derek Yuen and Nada Stefanovic and Josefa Pete and Coughlan, {Melinda T} and Karin Jandeleit-Dahm and Merlin Thomas and Franklin Rosenfeldt and Mark Cooper and {De Haan}, {Judy Bettina}",

year = "2010",

doi = "10.2337/db10-0195",

language = "English",

volume = "59",

pages = "3198--3207",

journal = "Diabetes",

issn = "0012-1797",

publisher = "American Diabetes Association",

number = "12",

}

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T1 - Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse

AU - Chew, Phyllis

AU - Yuen, Derek

AU - Stefanovic, Nada

AU - Pete, Josefa

AU - Coughlan, Melinda T

AU - Jandeleit-Dahm, Karin

AU - Thomas, Merlin

AU - Rosenfeldt, Franklin

AU - Cooper, Mark

AU - De Haan, Judy Bettina

PY - 2010

Y1 - 2010

N2 - To investigate the effect of the GPx1-mimetic ebselen on diabetes-associated atherosclerosis and renal injury in a model of increased oxidative stress.

AB - To investigate the effect of the GPx1-mimetic ebselen on diabetes-associated atherosclerosis and renal injury in a model of increased oxidative stress.

UR - http://diabetes.diabetesjournals.org/content/59/12/3198

U2 - 10.2337/db10-0195

DO - 10.2337/db10-0195

M3 - Article

SN - 0012-1797

VL - 59

SP - 3198

EP - 3207

JO - Diabetes

JF - Diabetes

IS - 12

ER -