Antenatal magnesium sulfate to prevent cerebral palsy

Amy K. Keir, Emily Shepherd, Sarah McIntyre, Alice Rumbold, Charlotte Groves, Caroline Crowther, Emily Joy Callander

Research output: Contribution to journalArticleResearchpeer-review


Magnesium sulfate given to women before birth at <30 weeks' gestation reduces the risk of cerebral palsy in their children. Our study aimed to assess the impact of a local quality improvement programme, primarily using plan-do-study-act cycles, to increase the use of antenatal magnesium sulfate. After implementing our quality improvement programme, an average of 86% of babies delivered at <30 weeks' gestation were exposed to antenatal magnesium sulfate compared with a historical baseline rate of 63%. Our study strengthens the case for embedding quality improvement programmes in maternal perinatal care to reduce the impact of cerebral palsy on families and society.

Original languageEnglish
Number of pages3
JournalArchives of Disease in Childhood: Fetal and Neonatal Edition
Publication statusAccepted/In press - 2021


  • health services research
  • neonatology

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