Anorectal malformation: the etiological factors

Chen Wang, Long Li, Wei Cheng

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Anorectal malformation (ARM) is a congenital anomaly commonly encountered in pediatric surgery practice. Although surgical procedures correct the anatomical anomalies, the post-operative bowel function is not universally satisfactory. The etiology of ARM remains unclear. In this review, we summarize the current understanding of the genetic and epigenetic factors contributing to the pathogenesis of ARM, based on published animal models, human genetics and epidemiological researches. Appreciation of these factors may be helpful in the management of ARM in the future.
Original languageEnglish
Pages (from-to)795 - 804
Number of pages10
JournalPediatric Surgery International
Volume31
Issue number9
DOIs
Publication statusPublished - 2015

Cite this

Wang, Chen ; Li, Long ; Cheng, Wei. / Anorectal malformation: the etiological factors. In: Pediatric Surgery International. 2015 ; Vol. 31, No. 9. pp. 795 - 804.
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Anorectal malformation: the etiological factors. / Wang, Chen; Li, Long; Cheng, Wei.

In: Pediatric Surgery International, Vol. 31, No. 9, 2015, p. 795 - 804.

Research output: Contribution to journalArticleResearchpeer-review

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