Angiotensin actions on and within brain

M. J. McKinley; A. M. Allen; B. J. Oldfield

doi:10.1016/B978-008045046-9.01164-5

Angiotensin actions on and within brain

M. J. McKinley, A. M. Allen, B. J. Oldfield

Physiology

Research output: Chapter in Book/Report/Conference proceeding › Encyclopaedia / Dictionary Entry › Other

Abstract

The renin-angiotensin system, via actions of its effector peptide angiotensin II, regulates body fluid balance and arterial pressure. Circulating angiotensin II acts on circumventricular organs of the brain to stimulate thirst, sodium appetite, vasopressin secretion, and sympathetic nerve activity, complementing its peripheral actions. Angiotensin II, III, and IV may also be generated within the brain, and a separate central angiotensinergic system may also participate in regulating body fluids and arterial pressure via angiotensin II receptors of the AT ₁ subtype.

Original language	English
Title of host publication	Encyclopedia of Neuroscience
Editors	L R Squire
Place of Publication	UK
Publisher	Elsevier
Pages	381-388
Number of pages	8
ISBN (Print)	9780080450469
DOIs	https://doi.org/10.1016/B978-008045046-9.01164-5
Publication status	Published - 1 Dec 2010

Keywords

Angiotensin II
AT receptors
Blood pressure
OVLT
Renal nerves
Renin
Salt appetite
Sodium
Subfornical organ
Thirst
Vasopressin
Ventrolateral medulla
Water intake

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10.1016/B978-008045046-9.01164-5

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abstract = "The renin-angiotensin system, via actions of its effector peptide angiotensin II, regulates body fluid balance and arterial pressure. Circulating angiotensin II acts on circumventricular organs of the brain to stimulate thirst, sodium appetite, vasopressin secretion, and sympathetic nerve activity, complementing its peripheral actions. Angiotensin II, III, and IV may also be generated within the brain, and a separate central angiotensinergic system may also participate in regulating body fluids and arterial pressure via angiotensin II receptors of the AT 1 subtype.",

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T1 - Angiotensin actions on and within brain

AU - McKinley, M. J.

AU - Allen, A. M.

AU - Oldfield, B. J.

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N2 - The renin-angiotensin system, via actions of its effector peptide angiotensin II, regulates body fluid balance and arterial pressure. Circulating angiotensin II acts on circumventricular organs of the brain to stimulate thirst, sodium appetite, vasopressin secretion, and sympathetic nerve activity, complementing its peripheral actions. Angiotensin II, III, and IV may also be generated within the brain, and a separate central angiotensinergic system may also participate in regulating body fluids and arterial pressure via angiotensin II receptors of the AT 1 subtype.

AB - The renin-angiotensin system, via actions of its effector peptide angiotensin II, regulates body fluid balance and arterial pressure. Circulating angiotensin II acts on circumventricular organs of the brain to stimulate thirst, sodium appetite, vasopressin secretion, and sympathetic nerve activity, complementing its peripheral actions. Angiotensin II, III, and IV may also be generated within the brain, and a separate central angiotensinergic system may also participate in regulating body fluids and arterial pressure via angiotensin II receptors of the AT 1 subtype.

KW - Angiotensin II

KW - AT receptors

KW - Blood pressure

KW - OVLT

KW - Renal nerves

KW - Renin

KW - Salt appetite

KW - Sodium

KW - Subfornical organ

KW - Thirst

KW - Vasopressin

KW - Ventrolateral medulla

KW - Water intake

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DO - 10.1016/B978-008045046-9.01164-5

M3 - Encyclopaedia / Dictionary Entry

SN - 9780080450469

SP - 381

EP - 388

BT - Encyclopedia of Neuroscience

A2 - Squire, L R

PB - Elsevier

CY - UK

ER -

Angiotensin actions on and within brain

Abstract

Keywords

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