Anethum graveolens L. supplementation has anti-inflammatory effect in type 2 diabetic patients

Laleh Payahoo; Alireza Ostadrahimi; Majid Mobasseri; Yaser Khaje Bishak; Mohammad Asghari Jafarabadi; Ali Baradaran Mahdavi; Sepide Mahluji

Anethum graveolens L. supplementation has anti-inflammatory effect in type 2 diabetic patients

Laleh Payahoo, Alireza Ostadrahimi, Majid Mobasseri, Yaser Khaje Bishak, Mohammad Asghari Jafarabadi, Ali Baradaran Mahdavi, Sepide Mahluji

Research output: Contribution to journal › Article › Research › peer-review

22 Citations (Scopus)

Abstract

This randomized, double-blind, placebo-controlled clinical trial designed to assess the effects of Anethum graveolens L. supplementation on the pro-inflammatory biomarkers (IL-6, TNF-α) and acute phase protein hs-CRP concentrations in type 2 diabetic patients. For 8 weeks, intervention group received 3.3 gm/day Anethum powder and placebo group received same amounts starch. At the onset and at the end of study collected 5 cc blood samples. The concentration of hs-CRP was measured by spectrophotometer method. IL-6 and TNF-α were assayed using ELISA method. Serum concentration of IL-6, TNF-α and hs-CRP decreased significantly at the end of study in intervention group (p<0.031, p<0.026, and p<0.045 respectively). Further clinical studies are needed to confirm the results.

Original language	English
Pages (from-to)	461-465
Number of pages	5
Journal	Indian Journal of Traditional Knowledge
Volume	13
Issue number	3
Publication status	Published - 2014
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Anethum graveolens
Diabetic patients
Inflammatory biomarkers

Cite this

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title = "Anethum graveolens L. supplementation has anti-inflammatory effect in type 2 diabetic patients",

abstract = "This randomized, double-blind, placebo-controlled clinical trial designed to assess the effects of Anethum graveolens L. supplementation on the pro-inflammatory biomarkers (IL-6, TNF-α) and acute phase protein hs-CRP concentrations in type 2 diabetic patients. For 8 weeks, intervention group received 3.3 gm/day Anethum powder and placebo group received same amounts starch. At the onset and at the end of study collected 5 cc blood samples. The concentration of hs-CRP was measured by spectrophotometer method. IL-6 and TNF-α were assayed using ELISA method. Serum concentration of IL-6, TNF-α and hs-CRP decreased significantly at the end of study in intervention group (p<0.031, p<0.026, and p<0.045 respectively). Further clinical studies are needed to confirm the results.",

keywords = "Anethum graveolens, Diabetic patients, Inflammatory biomarkers",

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T1 - Anethum graveolens L. supplementation has anti-inflammatory effect in type 2 diabetic patients

AU - Payahoo, Laleh

AU - Ostadrahimi, Alireza

AU - Mobasseri, Majid

AU - Bishak, Yaser Khaje

AU - Jafarabadi, Mohammad Asghari

AU - Mahdavi, Ali Baradaran

AU - Mahluji, Sepide

PY - 2014

Y1 - 2014

N2 - This randomized, double-blind, placebo-controlled clinical trial designed to assess the effects of Anethum graveolens L. supplementation on the pro-inflammatory biomarkers (IL-6, TNF-α) and acute phase protein hs-CRP concentrations in type 2 diabetic patients. For 8 weeks, intervention group received 3.3 gm/day Anethum powder and placebo group received same amounts starch. At the onset and at the end of study collected 5 cc blood samples. The concentration of hs-CRP was measured by spectrophotometer method. IL-6 and TNF-α were assayed using ELISA method. Serum concentration of IL-6, TNF-α and hs-CRP decreased significantly at the end of study in intervention group (p<0.031, p<0.026, and p<0.045 respectively). Further clinical studies are needed to confirm the results.

AB - This randomized, double-blind, placebo-controlled clinical trial designed to assess the effects of Anethum graveolens L. supplementation on the pro-inflammatory biomarkers (IL-6, TNF-α) and acute phase protein hs-CRP concentrations in type 2 diabetic patients. For 8 weeks, intervention group received 3.3 gm/day Anethum powder and placebo group received same amounts starch. At the onset and at the end of study collected 5 cc blood samples. The concentration of hs-CRP was measured by spectrophotometer method. IL-6 and TNF-α were assayed using ELISA method. Serum concentration of IL-6, TNF-α and hs-CRP decreased significantly at the end of study in intervention group (p<0.031, p<0.026, and p<0.045 respectively). Further clinical studies are needed to confirm the results.

KW - Anethum graveolens

KW - Diabetic patients

KW - Inflammatory biomarkers

UR - https://www.scopus.com/pages/publications/84904312143

M3 - Article

AN - SCOPUS:84904312143

SN - 0972-5938

VL - 13

SP - 461

EP - 465

JO - Indian Journal of Traditional Knowledge

JF - Indian Journal of Traditional Knowledge

IS - 3

ER -

Anethum graveolens L. supplementation has anti-inflammatory effect in type 2 diabetic patients

Abstract

UN SDGs

Keywords

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