Androgen Receptor Repeat Length Polymorphism Associated with Male-to-Female Transsexualism

Lauren May Hare, Pascal Bernard, Francisco J Sanchez, Paul N Baird, Eric Vilain, Trudy Kennedy, Vincent Russel Harley

Research output: Contribution to journalArticleResearchpeer-review

118 Citations (Scopus)

Abstract

There is a likely genetic component to transsexualism, and genes involved in sex steroidogenesis are good candidates. We explored the specific hypothesis that male-to-female transsexualism is associated with gene variants responsible for undermasculinization and/or feminization. Specifically, we assessed the role of disease-associated repeat length polymorphisms in the androgen receptor (AR), estrogen receptor ? (ER?), and aromatase (CYP19) genes.
Original languageEnglish
Pages (from-to)93 - 96
Number of pages4
JournalBiological Psychiatry
Volume65
Issue number1
DOIs
Publication statusPublished - 2009

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