Analysis of the incompatibility determinants of I-complex plasmids.

S. Nikoletti, P. Bird, J. Praszkier, J. Pittard

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The isolation and characterization of minireplicons corresponding to group B and I-complex plasmids are reported. The molecular structures of the small RNAs that may play a major role in the replication control and incompatibility reactions of the plasmids are compared. A mutant plasmid with changed copy number and incompatibility specificity is described. This mutant had a single-base-pair substitution in the DNA region that codes for the small RNA.

Original languageEnglish
Pages (from-to)1311-1318
Number of pages8
JournalJournal of Bacteriology
Issue number3
Publication statusPublished - 1 Jan 1988
Externally publishedYes

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