Analysis of linkage relationships in maturity-onset diabetes of young people and independent segregation of C6 and HLA

S. W. Serjeantson; P. Zimmet

doi:10.1007/BF00333521

Analysis of linkage relationships in maturity-onset diabetes of young people and independent segregation of C6 and HLA

S. W. Serjeantson, P. Zimmet

Research output: Contribution to journal › Article › Research › peer-review

6 Citations (Scopus)

Abstract

In a large kindred of maturity-onset diabetes of the young (MODY), 99 individuals were studied for 21 blood genetic markers. There were 17 informative systems in the pedigree and lod scores for AcPh, GLO1, C6, Gm and HLA excluded close linkage of these loci with MODY. The linkage relationships of C6 were also examined. C6 was not closely linked with the chromosome 6 markers HLA, Bf and GLO1, nor with AcPh, GPT, Hp, Tf, or Gm.

Original language	English
Pages (from-to)	214-216
Number of pages	3
Journal	Human Genetics
Volume	62
Issue number	3
DOIs	https://doi.org/10.1007/BF00333521
Publication status	Published - Dec 1982
Externally published	Yes

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10.1007/BF00333521

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abstract = "In a large kindred of maturity-onset diabetes of the young (MODY), 99 individuals were studied for 21 blood genetic markers. There were 17 informative systems in the pedigree and lod scores for AcPh, GLO1, C6, Gm and HLA excluded close linkage of these loci with MODY. The linkage relationships of C6 were also examined. C6 was not closely linked with the chromosome 6 markers HLA, Bf and GLO1, nor with AcPh, GPT, Hp, Tf, or Gm.",

author = "Serjeantson, {S. W.} and P. Zimmet",

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T1 - Analysis of linkage relationships in maturity-onset diabetes of young people and independent segregation of C6 and HLA

AU - Serjeantson, S. W.

AU - Zimmet, P.

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N2 - In a large kindred of maturity-onset diabetes of the young (MODY), 99 individuals were studied for 21 blood genetic markers. There were 17 informative systems in the pedigree and lod scores for AcPh, GLO1, C6, Gm and HLA excluded close linkage of these loci with MODY. The linkage relationships of C6 were also examined. C6 was not closely linked with the chromosome 6 markers HLA, Bf and GLO1, nor with AcPh, GPT, Hp, Tf, or Gm.

AB - In a large kindred of maturity-onset diabetes of the young (MODY), 99 individuals were studied for 21 blood genetic markers. There were 17 informative systems in the pedigree and lod scores for AcPh, GLO1, C6, Gm and HLA excluded close linkage of these loci with MODY. The linkage relationships of C6 were also examined. C6 was not closely linked with the chromosome 6 markers HLA, Bf and GLO1, nor with AcPh, GPT, Hp, Tf, or Gm.

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JO - Human Genetics

JF - Human Genetics

IS - 3

ER -

Analysis of linkage relationships in maturity-onset diabetes of young people and independent segregation of C6 and HLA

Abstract

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