Analysis of linkage relationships in maturity-onset diabetes of young people and independent segregation of C6 and HLA

S. W. Serjeantson, P. Zimmet

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In a large kindred of maturity-onset diabetes of the young (MODY), 99 individuals were studied for 21 blood genetic markers. There were 17 informative systems in the pedigree and lod scores for AcPh, GLO1, C6, Gm and HLA excluded close linkage of these loci with MODY. The linkage relationships of C6 were also examined. C6 was not closely linked with the chromosome 6 markers HLA, Bf and GLO1, nor with AcPh, GPT, Hp, Tf, or Gm.

Original languageEnglish
Pages (from-to)214-216
Number of pages3
JournalHuman Genetics
Issue number3
Publication statusPublished - Dec 1982
Externally publishedYes

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