Anal human papillomavirus infections in young unvaccinated men who have sex with men attending a sexual health clinic for HPV vaccination in Melbourne, Australia

Eric P.F. Chow, Jennifer A. Danielewski, Gerald L. Murray, Glenda Fehler, Marcus Y. Chen, Catriona S. Bradshaw, Suzanne M. Garland, Christopher K. Fairley

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Abstract

The Victorian Government introduced a time-limited quadrivalent human papillomavirus (HPV) vaccination catch-up program targeting gay and bisexual men who have sex with men (MSM) aged up to 26 years in 2017. As of 2017, men aged ≥20 years were not eligible for the school-based HPV vaccination program. This study examined the prevalence of anal HPV among 496 MSM aged 20–26 years before they received the first dose of the HPV vaccine at the Melbourne Sexual Health Centre, Australia. More than half (56.5%) had any high-risk HPV genotypes detected in the anus. Almost half (43.1%) had at least one quadrivalent HPV vaccine-preventable genotype (6, 11, 16 or 18) and one-fifth (21.0%) had HPV 16 detected in the anus. These findings suggest that a targeted catch-up HPV vaccination program for MSM is still beneficial to protect against high-risk HPV genotypes associated with anal cancer, as well as low-risk HPV genotypes.

Original languageEnglish
Pages (from-to)6271-6275
Number of pages5
JournalVaccine
Volume37
Issue number43
DOIs
Publication statusPublished - 8 Oct 2019

Keywords

  • Anal
  • Cancer
  • Catch-up program
  • Gay men
  • Homosexual
  • HPV
  • Human papillomavirus
  • MSM
  • Prevention
  • Vaccination
  • Vaccine

Cite this

@article{8a13461d2e314536a97d9b552c875a1f,
title = "Anal human papillomavirus infections in young unvaccinated men who have sex with men attending a sexual health clinic for HPV vaccination in Melbourne, Australia",
abstract = "The Victorian Government introduced a time-limited quadrivalent human papillomavirus (HPV) vaccination catch-up program targeting gay and bisexual men who have sex with men (MSM) aged up to 26 years in 2017. As of 2017, men aged ≥20 years were not eligible for the school-based HPV vaccination program. This study examined the prevalence of anal HPV among 496 MSM aged 20–26 years before they received the first dose of the HPV vaccine at the Melbourne Sexual Health Centre, Australia. More than half (56.5{\%}) had any high-risk HPV genotypes detected in the anus. Almost half (43.1{\%}) had at least one quadrivalent HPV vaccine-preventable genotype (6, 11, 16 or 18) and one-fifth (21.0{\%}) had HPV 16 detected in the anus. These findings suggest that a targeted catch-up HPV vaccination program for MSM is still beneficial to protect against high-risk HPV genotypes associated with anal cancer, as well as low-risk HPV genotypes.",
keywords = "Anal, Cancer, Catch-up program, Gay men, Homosexual, HPV, Human papillomavirus, MSM, Prevention, Vaccination, Vaccine",
author = "Chow, {Eric P.F.} and Danielewski, {Jennifer A.} and Murray, {Gerald L.} and Glenda Fehler and Chen, {Marcus Y.} and Bradshaw, {Catriona S.} and Garland, {Suzanne M.} and Fairley, {Christopher K.}",
year = "2019",
month = "10",
day = "8",
doi = "10.1016/j.vaccine.2019.08.066",
language = "English",
volume = "37",
pages = "6271--6275",
journal = "Vaccine",
issn = "0264-410X",
publisher = "Elsevier",
number = "43",

}

Anal human papillomavirus infections in young unvaccinated men who have sex with men attending a sexual health clinic for HPV vaccination in Melbourne, Australia. / Chow, Eric P.F.; Danielewski, Jennifer A.; Murray, Gerald L.; Fehler, Glenda; Chen, Marcus Y.; Bradshaw, Catriona S.; Garland, Suzanne M.; Fairley, Christopher K.

In: Vaccine, Vol. 37, No. 43, 08.10.2019, p. 6271-6275.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Anal human papillomavirus infections in young unvaccinated men who have sex with men attending a sexual health clinic for HPV vaccination in Melbourne, Australia

AU - Chow, Eric P.F.

AU - Danielewski, Jennifer A.

AU - Murray, Gerald L.

AU - Fehler, Glenda

AU - Chen, Marcus Y.

AU - Bradshaw, Catriona S.

AU - Garland, Suzanne M.

AU - Fairley, Christopher K.

PY - 2019/10/8

Y1 - 2019/10/8

N2 - The Victorian Government introduced a time-limited quadrivalent human papillomavirus (HPV) vaccination catch-up program targeting gay and bisexual men who have sex with men (MSM) aged up to 26 years in 2017. As of 2017, men aged ≥20 years were not eligible for the school-based HPV vaccination program. This study examined the prevalence of anal HPV among 496 MSM aged 20–26 years before they received the first dose of the HPV vaccine at the Melbourne Sexual Health Centre, Australia. More than half (56.5%) had any high-risk HPV genotypes detected in the anus. Almost half (43.1%) had at least one quadrivalent HPV vaccine-preventable genotype (6, 11, 16 or 18) and one-fifth (21.0%) had HPV 16 detected in the anus. These findings suggest that a targeted catch-up HPV vaccination program for MSM is still beneficial to protect against high-risk HPV genotypes associated with anal cancer, as well as low-risk HPV genotypes.

AB - The Victorian Government introduced a time-limited quadrivalent human papillomavirus (HPV) vaccination catch-up program targeting gay and bisexual men who have sex with men (MSM) aged up to 26 years in 2017. As of 2017, men aged ≥20 years were not eligible for the school-based HPV vaccination program. This study examined the prevalence of anal HPV among 496 MSM aged 20–26 years before they received the first dose of the HPV vaccine at the Melbourne Sexual Health Centre, Australia. More than half (56.5%) had any high-risk HPV genotypes detected in the anus. Almost half (43.1%) had at least one quadrivalent HPV vaccine-preventable genotype (6, 11, 16 or 18) and one-fifth (21.0%) had HPV 16 detected in the anus. These findings suggest that a targeted catch-up HPV vaccination program for MSM is still beneficial to protect against high-risk HPV genotypes associated with anal cancer, as well as low-risk HPV genotypes.

KW - Anal

KW - Cancer

KW - Catch-up program

KW - Gay men

KW - Homosexual

KW - HPV

KW - Human papillomavirus

KW - MSM

KW - Prevention

KW - Vaccination

KW - Vaccine

UR - http://www.scopus.com/inward/record.url?scp=85071980534&partnerID=8YFLogxK

U2 - 10.1016/j.vaccine.2019.08.066

DO - 10.1016/j.vaccine.2019.08.066

M3 - Article

VL - 37

SP - 6271

EP - 6275

JO - Vaccine

JF - Vaccine

SN - 0264-410X

IS - 43

ER -