An overview of the genetic variations of the sars-cov-2 genomes isolated in southeast asian countries

Polly Soo Xi Yap, Tse Siang Tan, Yoke Fun Chan, Kok Keng Tee, Adeeba Kamarulzaman, Cindy Shuan Ju Teh

Research output: Contribution to journalReview ArticleResearchpeer-review

6 Citations (Scopus)

Abstract

Monitoring the mutation dynamics of human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical in understanding its infectivity, virulence and pathogenicity for development of a vaccine. In an "age of mobility,"the pandemic highlights the importance and vulnerability of regionalization and labor market interdependence in Southeast Asia. We intend to characterize the genetic variability of viral populations within the region to provide preliminary information for regional surveillance in the future. By analyzing 142 complete genomes from South East Asian (SEA) countries, we identified three central variants distinguished by nucleotide and amino acid changes.

Original languageEnglish
Pages (from-to)962-966
Number of pages5
JournalJournal of Microbiology and Biotechnology
Volume30
Issue number7
DOIs
Publication statusPublished - 28 Jul 2020
Externally publishedYes

Keywords

  • Coronavirus
  • COVID-19
  • Genetic variation
  • Mutation
  • SARS-CoV-2
  • Southeast Asia

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