TY - JOUR
T1 - An overview of complementary and alternative medicine for Alzheimer's and Parkinson's disease
AU - Chong, Hui Ming
AU - Zulkaple, Mohamad Aidil Bin
AU - Chan, Hong Hao
AU - Lim, Chooi Ling
AU - Ng, Khuen Yen
AU - Ling, Anna Pick Kiong
AU - Chye, Soi Moi
AU - Koh, Rhun Yian
N1 - Funding Information:
This review was supported in part by the Ministry of Higher Education, Malaysia [grant no. FRGS/2/2014/SKK01/MUSM/03/1].
Publisher Copyright:
© 2021 Malaysian Society for Biochemistry and Molecular Biology. All rights reserved.
PY - 2021/8
Y1 - 2021/8
N2 - Parkinson s disease (PD) and Alzheimer s disease (AD) are two common neurodegenerative diseases that primarily affect the elderly population. AD causes dementia and is associated with disrupted brain structure and function, and its classical hallmarks include the accumulation of the beta-Amyloid plaques and build-up of tau tangles. On the other hand, PD features a myriad of motor aberrations characterised by tremors, postural instability, rigidity, and bradykinesia as a result of the loss of dopaminergic neurons in the brain. Currently, available treatment regimens for AD and PD show limited efficacy in alleviating the symptoms or reversing pathogenesis. Inadvertently, several complementary and alternative medicine (CAM) methods have been linked to symptomatic relief for both conditions. These CAM approaches include the utilisation of natural products, nutritional supplements, acupuncture, and exercise. In this review, a repertoire of CAM therapies and their effectiveness in alleviating AD and PD are discussed.
AB - Parkinson s disease (PD) and Alzheimer s disease (AD) are two common neurodegenerative diseases that primarily affect the elderly population. AD causes dementia and is associated with disrupted brain structure and function, and its classical hallmarks include the accumulation of the beta-Amyloid plaques and build-up of tau tangles. On the other hand, PD features a myriad of motor aberrations characterised by tremors, postural instability, rigidity, and bradykinesia as a result of the loss of dopaminergic neurons in the brain. Currently, available treatment regimens for AD and PD show limited efficacy in alleviating the symptoms or reversing pathogenesis. Inadvertently, several complementary and alternative medicine (CAM) methods have been linked to symptomatic relief for both conditions. These CAM approaches include the utilisation of natural products, nutritional supplements, acupuncture, and exercise. In this review, a repertoire of CAM therapies and their effectiveness in alleviating AD and PD are discussed.
KW - Alzheimer s disease
KW - Complementary and alternative medicine
KW - Parkinson s disease
UR - http://www.scopus.com/inward/record.url?scp=85117962863&partnerID=8YFLogxK
M3 - Review Article
AN - SCOPUS:85117962863
SN - 1511-2616
VL - 24
SP - 36
EP - 53
JO - Malaysian Journal of Biochemistry & Molecular Biology
JF - Malaysian Journal of Biochemistry & Molecular Biology
IS - 2
ER -