An efficient synthesis of the opioid analgesic (R)-phenampromide via an aziridinium ion

Mohammad Mujahid; Prashant Mujumdar; Murugesan Sasikumar; Shirish P. Deshmukh; Murugan Muthukrishnan

doi:10.1016/j.tetasy.2017.06.001

An efficient synthesis of the opioid analgesic (R)-phenampromide via an aziridinium ion

Mohammad Mujahid, Prashant Mujumdar, Murugesan Sasikumar, Shirish P. Deshmukh, Murugan Muthukrishnan

Research output: Contribution to journal › Article › Research › peer-review

6 Citations (Scopus)

Abstract

A simple and efficient synthesis of the opioid analgesic agent (R)-phenampromide with high enantiopurity (>99% ee) via the formation of an aziridinium ion as a key step using commercially available starting material is described.

Original language	English
Pages (from-to)	983-986
Number of pages	4
Journal	Tetrahedron Asymmetry
Volume	28
Issue number	7
DOIs	https://doi.org/10.1016/j.tetasy.2017.06.001
Publication status	Published - 1 Jan 2017
Externally published	Yes

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title = "An efficient synthesis of the opioid analgesic (R)-phenampromide via an aziridinium ion",

abstract = "A simple and efficient synthesis of the opioid analgesic agent (R)-phenampromide with high enantiopurity (>99\% ee) via the formation of an aziridinium ion as a key step using commercially available starting material is described.",

author = "Mohammad Mujahid and Prashant Mujumdar and Murugesan Sasikumar and Deshmukh, \{Shirish P.\} and Murugan Muthukrishnan",

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AU - Mujahid, Mohammad

AU - Mujumdar, Prashant

AU - Sasikumar, Murugesan

AU - Deshmukh, Shirish P.

AU - Muthukrishnan, Murugan

PY - 2017/1/1

Y1 - 2017/1/1

N2 - A simple and efficient synthesis of the opioid analgesic agent (R)-phenampromide with high enantiopurity (>99% ee) via the formation of an aziridinium ion as a key step using commercially available starting material is described.

AB - A simple and efficient synthesis of the opioid analgesic agent (R)-phenampromide with high enantiopurity (>99% ee) via the formation of an aziridinium ion as a key step using commercially available starting material is described.

UR - https://www.scopus.com/pages/publications/85020489506

U2 - 10.1016/j.tetasy.2017.06.001

DO - 10.1016/j.tetasy.2017.06.001

M3 - Article

AN - SCOPUS:85020489506

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SP - 983

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JO - Tetrahedron Asymmetry

JF - Tetrahedron Asymmetry

IS - 7

ER -

An efficient synthesis of the opioid analgesic (R)-phenampromide via an aziridinium ion

Abstract

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