An efficient synthesis of the opioid analgesic (R)-phenampromide via an aziridinium ion

Mohammad Mujahid, Prashant Mujumdar, Murugesan Sasikumar, Shirish P. Deshmukh, Murugan Muthukrishnan

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4 Citations (Scopus)

Abstract

A simple and efficient synthesis of the opioid analgesic agent (R)-phenampromide with high enantiopurity (>99% ee) via the formation of an aziridinium ion as a key step using commercially available starting material is described.

Original languageEnglish
Pages (from-to)983-986
Number of pages4
JournalTetrahedron Asymmetry
Volume28
Issue number7
DOIs
Publication statusPublished - 1 Jan 2017
Externally publishedYes

Cite this

Mujahid, M., Mujumdar, P., Sasikumar, M., Deshmukh, S. P., & Muthukrishnan, M. (2017). An efficient synthesis of the opioid analgesic (R)-phenampromide via an aziridinium ion. Tetrahedron Asymmetry, 28(7), 983-986. https://doi.org/10.1016/j.tetasy.2017.06.001