An economic analysis of patient controlled remifentanil and epidural analgesia as pain relief in labour (RAVEL trial); A randomised controlled trial.

Liv Freeman, Johanna Middeldorp, Eline Van Den Akker, Martijn Oudijk, Caroline Bax, Marloes Van Huizen, Celine Radder, Bianca Fong, Kitty Bloemenkamp, Albert Dahan, Michel Struys, Ben Willem Mol, Jan Van Lith, Elske Van Den Akker-Van Marle

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Objective To compare the costs of a strategy of patient controlled remifentanil versus epidural analgesia for pain relief in labour. Design We performed a multicentre randomised controlled trial in 15 hospitals in the Netherlands, The RAVEL trial. Costs were analysed from a health care perspective alongside the RAVEL trial. Population Pregnant women of intermediate to high risk beyond 32 weeks gestation who planned vaginal delivery. Methods Women were randomised before the onset of labour, to receive either patient controlled remifentanil or epidural analgesia when pain relief was requested during labour.

Original languageEnglish
Article numbere0205220
Number of pages13
JournalPLoS ONE
Issue number10
Publication statusPublished - 1 Oct 2018
Externally publishedYes

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