An atlas of serpin conformations

James Whisstock; Richard Skinner; Arthur M. Lesk

doi:10.1016/S0968-0004(97)01172-9

An atlas of serpin conformations

James Whisstock, Richard Skinner, Arthur M. Lesk

Research output: Contribution to journal › Review Article › Research › peer-review

168 Citations (Scopus)

Abstract

The serpins are a family of proteins that inhibit chymotrypsin-like serine proteinases, with an unusual mechanism involving a large conformational change known as the stressed→relaxed (S→R) transition. This article is a guide to the known serpin conformations and their biological significance.

Original language	English
Pages (from-to)	63-67
Number of pages	5
Journal	Trends in Biochemical Sciences
Volume	23
Issue number	2
DOIs	https://doi.org/10.1016/S0968-0004(97)01172-9
Publication status	Published - Feb 1998
Externally published	Yes

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10.1016/S0968-0004(97)01172-9

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title = "An atlas of serpin conformations",

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JO - Trends in Biochemical Sciences

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An atlas of serpin conformations

Abstract

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