An aggregation-induced emission (AIE) ratiometric fluorescent cysteine probe with an exceptionally large blue shift

Liqiang Yan; Zhineng Kong; Wei Shen; Wenqi Du; Yan Zhou; Zhengjian Qi

doi:10.1039/c5ra22245a

An aggregation-induced emission (AIE) ratiometric fluorescent cysteine probe with an exceptionally large blue shift

Liqiang Yan, Zhineng Kong, Wei Shen, Wenqi Du, Yan Zhou, Zhengjian Qi

Research output: Contribution to journal › Article › Research › peer-review

20 Citations (Scopus)

Abstract

In this work, we developed a novel colorimetric and ratiometric fluorescence probe for the selective and sensitive monitoring of cysteine based on a coumarin Schiff-base platform. This probe exhibited remarkable AIE characteristics with an exceptionally large blue shift (125 nm), which showed low emission in DMSO but strong aggregation-induced emission in water solution. An excellent linear relationship of fluorescence intensity ratio (F₄₅₀/F₅₇₅) (R² = 0.9922) versus Cys concentration in the range of 1-13 μM was obtained.

Original language	English
Pages (from-to)	5636-5640
Number of pages	5
Journal	RSC Advances
Volume	6
Issue number	7
DOIs	https://doi.org/10.1039/c5ra22245a
Publication status	Published - 2016
Externally published	Yes

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abstract = "In this work, we developed a novel colorimetric and ratiometric fluorescence probe for the selective and sensitive monitoring of cysteine based on a coumarin Schiff-base platform. This probe exhibited remarkable AIE characteristics with an exceptionally large blue shift (125 nm), which showed low emission in DMSO but strong aggregation-induced emission in water solution. An excellent linear relationship of fluorescence intensity ratio (F450/F575) (R2 = 0.9922) versus Cys concentration in the range of 1-13 μM was obtained.",

author = "Liqiang Yan and Zhineng Kong and Wei Shen and Wenqi Du and Yan Zhou and Zhengjian Qi",

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T1 - An aggregation-induced emission (AIE) ratiometric fluorescent cysteine probe with an exceptionally large blue shift

AU - Yan, Liqiang

AU - Kong, Zhineng

AU - Shen, Wei

AU - Du, Wenqi

AU - Zhou, Yan

AU - Qi, Zhengjian

PY - 2016

Y1 - 2016

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AB - In this work, we developed a novel colorimetric and ratiometric fluorescence probe for the selective and sensitive monitoring of cysteine based on a coumarin Schiff-base platform. This probe exhibited remarkable AIE characteristics with an exceptionally large blue shift (125 nm), which showed low emission in DMSO but strong aggregation-induced emission in water solution. An excellent linear relationship of fluorescence intensity ratio (F450/F575) (R2 = 0.9922) versus Cys concentration in the range of 1-13 μM was obtained.

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U2 - 10.1039/c5ra22245a

DO - 10.1039/c5ra22245a

M3 - Article

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JO - RSC Advances

JF - RSC Advances

SN - 2046-2069

IS - 7

ER -

An aggregation-induced emission (AIE) ratiometric fluorescent cysteine probe with an exceptionally large blue shift

Abstract

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