An aggregation-induced emission (AIE) ratiometric fluorescent cysteine probe with an exceptionally large blue shift

Liqiang Yan, Zhineng Kong, Wei Shen, Wenqi Du, Yan Zhou, Zhengjian Qi

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Abstract

In this work, we developed a novel colorimetric and ratiometric fluorescence probe for the selective and sensitive monitoring of cysteine based on a coumarin Schiff-base platform. This probe exhibited remarkable AIE characteristics with an exceptionally large blue shift (125 nm), which showed low emission in DMSO but strong aggregation-induced emission in water solution. An excellent linear relationship of fluorescence intensity ratio (F450/F575) (R2 = 0.9922) versus Cys concentration in the range of 1-13 μM was obtained.

Original languageEnglish
Pages (from-to)5636-5640
Number of pages5
JournalRSC Advances
Volume6
Issue number7
DOIs
Publication statusPublished - 2016
Externally publishedYes

Cite this

Yan, Liqiang ; Kong, Zhineng ; Shen, Wei ; Du, Wenqi ; Zhou, Yan ; Qi, Zhengjian. / An aggregation-induced emission (AIE) ratiometric fluorescent cysteine probe with an exceptionally large blue shift. In: RSC Advances. 2016 ; Vol. 6, No. 7. pp. 5636-5640.
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An aggregation-induced emission (AIE) ratiometric fluorescent cysteine probe with an exceptionally large blue shift. / Yan, Liqiang; Kong, Zhineng; Shen, Wei; Du, Wenqi; Zhou, Yan; Qi, Zhengjian.

In: RSC Advances, Vol. 6, No. 7, 2016, p. 5636-5640.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - An aggregation-induced emission (AIE) ratiometric fluorescent cysteine probe with an exceptionally large blue shift

AU - Yan, Liqiang

AU - Kong, Zhineng

AU - Shen, Wei

AU - Du, Wenqi

AU - Zhou, Yan

AU - Qi, Zhengjian

PY - 2016

Y1 - 2016

N2 - In this work, we developed a novel colorimetric and ratiometric fluorescence probe for the selective and sensitive monitoring of cysteine based on a coumarin Schiff-base platform. This probe exhibited remarkable AIE characteristics with an exceptionally large blue shift (125 nm), which showed low emission in DMSO but strong aggregation-induced emission in water solution. An excellent linear relationship of fluorescence intensity ratio (F450/F575) (R2 = 0.9922) versus Cys concentration in the range of 1-13 μM was obtained.

AB - In this work, we developed a novel colorimetric and ratiometric fluorescence probe for the selective and sensitive monitoring of cysteine based on a coumarin Schiff-base platform. This probe exhibited remarkable AIE characteristics with an exceptionally large blue shift (125 nm), which showed low emission in DMSO but strong aggregation-induced emission in water solution. An excellent linear relationship of fluorescence intensity ratio (F450/F575) (R2 = 0.9922) versus Cys concentration in the range of 1-13 μM was obtained.

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U2 - 10.1039/c5ra22245a

DO - 10.1039/c5ra22245a

M3 - Article

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