AN ACOUSTICALLY DRIVEN PLASMA SEPARATION SYSTEM WITH SHORT PROCESS TIME AND PORTABILITY FOR POC MEDICAL DEVICES

Kamal Prakash Prasanna Ravindran Nair; Thulya Chakkumpulakkal Puthan Veettil; Bayden R. Wood; Debjani Paul; Tuncay Alan

AN ACOUSTICALLY DRIVEN PLASMA SEPARATION SYSTEM WITH SHORT PROCESS TIME AND PORTABILITY FOR POC MEDICAL DEVICES

Kamal Prakash Prasanna Ravindran Nair, Thulya Chakkumpulakkal Puthan Veettil, Bayden R. Wood, Debjani Paul, Tuncay Alan

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Other

Abstract

We present a SAW-based platform with a portable actuator towards the separation of plasma from 20-fold diluted blood. The process could be resolved within 135 sec and the repeatability of the same was studied using ATR-FTIR spectroscopy (wherein the device-derived plasma was compared to centrifuge-derived plasma). The SAW-chip showed >90% separation of RBC and plasma components while the RBC count in the process chamber post-process indicated ca. 98% collection. Furthermore, the similarity of the samples from different runs was also virtually identical to that obtained from centrifugation.

Original language	English
Title of host publication	MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Publisher	Chemical and Biological Microsystems Society
Pages	877-878
Number of pages	2
ISBN (Electronic)	9781733419031
Publication status	Published - 2021
Event	International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2021) - Online, Palm Springs, United States of America Duration: 10 Oct 2021 → 14 Oct 2021 Conference number: 25th https://microtas2021.org/about/conference_info.html (Wesbite)

Conference

Conference	International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2021)
Abbreviated title	MicroTAS 2021
Country/Territory	United States of America
City	Palm Springs
Period	10/10/21 → 14/10/21
Internet address	https://microtas2021.org/about/conference_info.html (Wesbite)

Keywords

harmonic-interdigitated transducers
particle collection/sorting
plasma separation
point-of-care diagnostics
SAW open-microfluidics

Cite this

Nair, Kamal Prakash Prasanna Ravindran ; Veettil, Thulya Chakkumpulakkal Puthan ; Wood, Bayden R. et al. / AN ACOUSTICALLY DRIVEN PLASMA SEPARATION SYSTEM WITH SHORT PROCESS TIME AND PORTABILITY FOR POC MEDICAL DEVICES. MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2021. pp. 877-878

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title = "AN ACOUSTICALLY DRIVEN PLASMA SEPARATION SYSTEM WITH SHORT PROCESS TIME AND PORTABILITY FOR POC MEDICAL DEVICES",

abstract = "We present a SAW-based platform with a portable actuator towards the separation of plasma from 20-fold diluted blood. The process could be resolved within 135 sec and the repeatability of the same was studied using ATR-FTIR spectroscopy (wherein the device-derived plasma was compared to centrifuge-derived plasma). The SAW-chip showed >90% separation of RBC and plasma components while the RBC count in the process chamber post-process indicated ca. 98% collection. Furthermore, the similarity of the samples from different runs was also virtually identical to that obtained from centrifugation.",

keywords = "harmonic-interdigitated transducers, particle collection/sorting, plasma separation, point-of-care diagnostics, SAW open-microfluidics",

author = "Nair, {Kamal Prakash Prasanna Ravindran} and Veettil, {Thulya Chakkumpulakkal Puthan} and Wood, {Bayden R.} and Debjani Paul and Tuncay Alan",

note = "Publisher Copyright: {\textcopyright} 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.; International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2021), MicroTAS 2021 ; Conference date: 10-10-2021 Through 14-10-2021",

year = "2021",

language = "English",

pages = "877--878",

booktitle = "MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences",

publisher = "Chemical and Biological Microsystems Society",

address = "United States of America",

url = "https://microtas2021.org/about/conference_info.html",

}

Nair, KPPR, Veettil, TCP, Wood, BR, Paul, D & Alan, T 2021, AN ACOUSTICALLY DRIVEN PLASMA SEPARATION SYSTEM WITH SHORT PROCESS TIME AND PORTABILITY FOR POC MEDICAL DEVICES. in MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, pp. 877-878, International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2021), Palm Springs, California, United States of America, 10/10/21.

AN ACOUSTICALLY DRIVEN PLASMA SEPARATION SYSTEM WITH SHORT PROCESS TIME AND PORTABILITY FOR POC MEDICAL DEVICES. / Nair, Kamal Prakash Prasanna Ravindran; Veettil, Thulya Chakkumpulakkal Puthan; Wood, Bayden R. et al.
MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2021. p. 877-878.

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Other

TY - GEN

T1 - AN ACOUSTICALLY DRIVEN PLASMA SEPARATION SYSTEM WITH SHORT PROCESS TIME AND PORTABILITY FOR POC MEDICAL DEVICES

AU - Nair, Kamal Prakash Prasanna Ravindran

AU - Veettil, Thulya Chakkumpulakkal Puthan

AU - Wood, Bayden R.

AU - Paul, Debjani

AU - Alan, Tuncay

N1 - Conference code: 25th

PY - 2021

Y1 - 2021

N2 - We present a SAW-based platform with a portable actuator towards the separation of plasma from 20-fold diluted blood. The process could be resolved within 135 sec and the repeatability of the same was studied using ATR-FTIR spectroscopy (wherein the device-derived plasma was compared to centrifuge-derived plasma). The SAW-chip showed >90% separation of RBC and plasma components while the RBC count in the process chamber post-process indicated ca. 98% collection. Furthermore, the similarity of the samples from different runs was also virtually identical to that obtained from centrifugation.

AB - We present a SAW-based platform with a portable actuator towards the separation of plasma from 20-fold diluted blood. The process could be resolved within 135 sec and the repeatability of the same was studied using ATR-FTIR spectroscopy (wherein the device-derived plasma was compared to centrifuge-derived plasma). The SAW-chip showed >90% separation of RBC and plasma components while the RBC count in the process chamber post-process indicated ca. 98% collection. Furthermore, the similarity of the samples from different runs was also virtually identical to that obtained from centrifugation.

KW - harmonic-interdigitated transducers

KW - particle collection/sorting

KW - plasma separation

KW - point-of-care diagnostics

KW - SAW open-microfluidics

UR - http://www.scopus.com/inward/record.url?scp=85136954106&partnerID=8YFLogxK

M3 - Conference Paper

AN - SCOPUS:85136954106

SP - 877

EP - 878

BT - MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

PB - Chemical and Biological Microsystems Society

T2 - International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2021)

Y2 - 10 October 2021 through 14 October 2021

ER -

AN ACOUSTICALLY DRIVEN PLASMA SEPARATION SYSTEM WITH SHORT PROCESS TIME AND PORTABILITY FOR POC MEDICAL DEVICES

Abstract

Conference

Keywords

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Cite this