AMP-activated protein kinase, super metabolic regulator

Bruce E Kemp, David Stapleton, Duncan J Campbell, Z-P Chen, S Murthy, Mark Walter, A Gupta, Julian J Adams, Frosa Katsis, Bryce JW van Denderen, Ian G Jennings, Tristan J Iseli, Belinda J Michell, L A Witters

Research output: Contribution to journalArticleResearchpeer-review

364 Citations (Scopus)

Abstract

The AMP-activated protein kinase (AMPK) is a metabolic-stress-sensing protein kinase that regulates metabolism in response to energy demand and supply by directly phosphorylating rate-limiting enzymes in metabolic pathways as well as controlling gene expression.
Original languageEnglish
Pages (from-to)162 - 168
Number of pages7
JournalBiochemical Society Transactions
Volume31
Issue numberPt 1
Publication statusPublished - 2003

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