?-Amino acid-containing hybrid peptides - New opportunities in peptidomimetics

Marie Isabel Aguilar, Anthony Wayne Purcell, Romila Devi, Rebecca Ann Lew, Jamie Rossjohn, Alexander Ian Smith, Patrick Perlmutter

Research output: Contribution to journalArticleResearchpeer-review

85 Citations (Scopus)

Abstract

Hybrid peptides consisting of alpha-amino acids with judiciously placed beta-amino acids show great promise as peptidomimetics in an increasing range of therapeutic applications. This reflects a combination of increased stability, high specificity and relative ease of synthesis.
Original languageEnglish
Pages (from-to)2884 - 2890
Number of pages7
JournalOrganic and Biomolecular Chemistry
Volume5
Issue number18
Publication statusPublished - 2007

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