?-Amino acid-containing hybrid peptides - New opportunities in peptidomimetics

Marie Isabel Aguilar, Anthony Wayne Purcell, Romila Devi, Rebecca Ann Lew, Jamie Rossjohn, Alexander Ian Smith, Patrick Perlmutter

Research output: Contribution to journalArticleResearchpeer-review

77 Citations (Scopus)

Abstract

Hybrid peptides consisting of alpha-amino acids with judiciously placed beta-amino acids show great promise as peptidomimetics in an increasing range of therapeutic applications. This reflects a combination of increased stability, high specificity and relative ease of synthesis.
Original languageEnglish
Pages (from-to)2884 - 2890
Number of pages7
JournalOrganic and Biomolecular Chemistry
Volume5
Issue number18
Publication statusPublished - 2007

Cite this

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title = "?-Amino acid-containing hybrid peptides - New opportunities in peptidomimetics",
abstract = "Hybrid peptides consisting of alpha-amino acids with judiciously placed beta-amino acids show great promise as peptidomimetics in an increasing range of therapeutic applications. This reflects a combination of increased stability, high specificity and relative ease of synthesis.",
author = "Aguilar, {Marie Isabel} and Purcell, {Anthony Wayne} and Romila Devi and Lew, {Rebecca Ann} and Jamie Rossjohn and Smith, {Alexander Ian} and Patrick Perlmutter",
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?-Amino acid-containing hybrid peptides - New opportunities in peptidomimetics. / Aguilar, Marie Isabel; Purcell, Anthony Wayne; Devi, Romila; Lew, Rebecca Ann; Rossjohn, Jamie; Smith, Alexander Ian; Perlmutter, Patrick.

In: Organic and Biomolecular Chemistry, Vol. 5, No. 18, 2007, p. 2884 - 2890.

Research output: Contribution to journalArticleResearchpeer-review

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AU - Aguilar, Marie Isabel

AU - Purcell, Anthony Wayne

AU - Devi, Romila

AU - Lew, Rebecca Ann

AU - Rossjohn, Jamie

AU - Smith, Alexander Ian

AU - Perlmutter, Patrick

PY - 2007

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AB - Hybrid peptides consisting of alpha-amino acids with judiciously placed beta-amino acids show great promise as peptidomimetics in an increasing range of therapeutic applications. This reflects a combination of increased stability, high specificity and relative ease of synthesis.

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EP - 2890

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

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