Abstract
No evidence exists concerning the association between blood pressure and ambient particles with aerodynamic diameter ≤ 1.0 µm (PM1), a major component of PM2.5 (≤ 2.5 µm) particles, and potentially causing more hazardous health effects than PM2.5. We aimed to examine the associations of blood pressure in adults with both PM1 and PM2.5 in China. In 2009, we randomly selected 24,845 participants aged 18–74 years from 33 communities in China. Using a standardized mercuric-column sphygmomanometer, we measured blood pressure. Long-term exposure (2006–08) to PM1 and PM2.5 were estimated using a spatial statistical model. Generalized linear mixed models were used to evaluate the associations between air pollutants and blood pressure and hypertension prevalence, controlling for multiple covariates. A 10-μg/m3 increase in PM1 was significantly associated with an increase of 0.57 (95% CI 0.31–0.83) mmHg in systolic blood pressure (SBP), 0.19 (95% CI 0.03–0.35) mmHg increase in diastolic blood pressure (DBP), and a 5% (OR=1.05; 95% CI 1.01–1.10) increase in odds for hypertension. Similar associations were detected for PM2.5. Furthermore, PM1–2.5 showed no association with blood pressure or hypertension. In summary, both PM1 and PM2.5 exposures were associated with elevated blood pressure levels and hypertension prevalence in Chinese adults. In addition, most of the pro-hypertensive effects of PM2.5 may come from PM1. Further longitudinal designed studies are warranted to validate our findings.
| Original language | English |
|---|---|
| Pages (from-to) | 252-259 |
| Number of pages | 8 |
| Journal | Environmental Research |
| Volume | 170 |
| DOIs | |
| Publication status | Published - 1 Mar 2019 |
Keywords
- Adults
- Cross-sectional study
- Diastolic blood pressure
- Particulate matter
- Systolic blood pressure
Cite this
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Ambient PM1 air pollution, blood pressure, and hypertension : Insights from the 33 Communities Chinese Health Study. / Yang, Bo Yi; Guo, Yuming; Bloom, Michael S.; Xiao, Xiang; Qian, Zhengmin (Min); Liu, Echu; Howard, Steven W.; Zhao, Tianyu; Wang, Si Quan; Li, Shanshan; Chen, Duo Hong; Ma, Huimin; Yim, Steve Hung Lam; Liu, Kang Kang; Zeng, Xiao Wen; Hu, Li Wen; Liu, Ru Qing; Feng, Dan; Yang, Mo; Xu, Shu Li; Dong, Guang Hui.
In: Environmental Research, Vol. 170, 01.03.2019, p. 252-259.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Ambient PM1 air pollution, blood pressure, and hypertension
T2 - Insights from the 33 Communities Chinese Health Study
AU - Yang, Bo Yi
AU - Guo, Yuming
AU - Bloom, Michael S.
AU - Xiao, Xiang
AU - Qian, Zhengmin (Min)
AU - Liu, Echu
AU - Howard, Steven W.
AU - Zhao, Tianyu
AU - Wang, Si Quan
AU - Li, Shanshan
AU - Chen, Duo Hong
AU - Ma, Huimin
AU - Yim, Steve Hung Lam
AU - Liu, Kang Kang
AU - Zeng, Xiao Wen
AU - Hu, Li Wen
AU - Liu, Ru Qing
AU - Feng, Dan
AU - Yang, Mo
AU - Xu, Shu Li
AU - Dong, Guang Hui
PY - 2019/3/1
Y1 - 2019/3/1
N2 - No evidence exists concerning the association between blood pressure and ambient particles with aerodynamic diameter ≤ 1.0 µm (PM1), a major component of PM2.5 (≤ 2.5 µm) particles, and potentially causing more hazardous health effects than PM2.5. We aimed to examine the associations of blood pressure in adults with both PM1 and PM2.5 in China. In 2009, we randomly selected 24,845 participants aged 18–74 years from 33 communities in China. Using a standardized mercuric-column sphygmomanometer, we measured blood pressure. Long-term exposure (2006–08) to PM1 and PM2.5 were estimated using a spatial statistical model. Generalized linear mixed models were used to evaluate the associations between air pollutants and blood pressure and hypertension prevalence, controlling for multiple covariates. A 10-μg/m3 increase in PM1 was significantly associated with an increase of 0.57 (95% CI 0.31–0.83) mmHg in systolic blood pressure (SBP), 0.19 (95% CI 0.03–0.35) mmHg increase in diastolic blood pressure (DBP), and a 5% (OR=1.05; 95% CI 1.01–1.10) increase in odds for hypertension. Similar associations were detected for PM2.5. Furthermore, PM1–2.5 showed no association with blood pressure or hypertension. In summary, both PM1 and PM2.5 exposures were associated with elevated blood pressure levels and hypertension prevalence in Chinese adults. In addition, most of the pro-hypertensive effects of PM2.5 may come from PM1. Further longitudinal designed studies are warranted to validate our findings.
AB - No evidence exists concerning the association between blood pressure and ambient particles with aerodynamic diameter ≤ 1.0 µm (PM1), a major component of PM2.5 (≤ 2.5 µm) particles, and potentially causing more hazardous health effects than PM2.5. We aimed to examine the associations of blood pressure in adults with both PM1 and PM2.5 in China. In 2009, we randomly selected 24,845 participants aged 18–74 years from 33 communities in China. Using a standardized mercuric-column sphygmomanometer, we measured blood pressure. Long-term exposure (2006–08) to PM1 and PM2.5 were estimated using a spatial statistical model. Generalized linear mixed models were used to evaluate the associations between air pollutants and blood pressure and hypertension prevalence, controlling for multiple covariates. A 10-μg/m3 increase in PM1 was significantly associated with an increase of 0.57 (95% CI 0.31–0.83) mmHg in systolic blood pressure (SBP), 0.19 (95% CI 0.03–0.35) mmHg increase in diastolic blood pressure (DBP), and a 5% (OR=1.05; 95% CI 1.01–1.10) increase in odds for hypertension. Similar associations were detected for PM2.5. Furthermore, PM1–2.5 showed no association with blood pressure or hypertension. In summary, both PM1 and PM2.5 exposures were associated with elevated blood pressure levels and hypertension prevalence in Chinese adults. In addition, most of the pro-hypertensive effects of PM2.5 may come from PM1. Further longitudinal designed studies are warranted to validate our findings.
KW - Adults
KW - Cross-sectional study
KW - Diastolic blood pressure
KW - Particulate matter
KW - Systolic blood pressure
UR - http://www.scopus.com/inward/record.url?scp=85059189947&partnerID=8YFLogxK
U2 - 10.1016/j.envres.2018.12.047
DO - 10.1016/j.envres.2018.12.047
M3 - Article
AN - SCOPUS:85059189947
VL - 170
SP - 252
EP - 259
JO - Environmental Research
JF - Environmental Research
SN - 0013-9351
ER -