Alternating lodonium-mediated reaction cascades giving indole- And quinoline-containing polycycles

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A simple two-step convergent protocol gives direct access to synthetic intermediate A from ortho-iodoanilines. Intermediate A can be treated with NIS in CH2Cl2 to induce novel iodonium mediated domino reaction cascade, which provides direct access to ring-fused indole compounds B. Simply by changing the reaction conditions, this protocol can be directed down an alternative domino reaction cascade to give various ring fused quinoline compounds C.
Original languageEnglish
Pages (from-to)1967 - 1970
Number of pages4
JournalOrganic Letters
Issue number10
Publication statusPublished - 2008

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