Altered kinetics and benzodiazepine sensitivity of a GABAA receptor subunit mutation [2(R43Q)] found in human epilepsy

David N Bowser; David A Wagner; Cynthia Czajkowski; Brett A Cromer; Michael W Parker; Robyn H Wallace; Louise A Harkin; John C Mulley; Carla Marini; Samuel F Berkovic; David A Williams; Mathew V Jones; Steven Petrou

doi:10.1073/pnas.212320199

Altered kinetics and benzodiazepine sensitivity of a GABAA receptor subunit mutation [2(R43Q)] found in human epilepsy

David N Bowser
, David A Wagner
, Cynthia Czajkowski
, Brett A Cromer
, Michael W Parker
, Robyn H Wallace
, Louise A Harkin
, John C Mulley
, Carla Marini
, Samuel F Berkovic
, David A Williams
, Mathew V Jones
, Steven Petrou

Biochemistry & Molecular Biology

Research output: Contribution to journal › Article › Research › peer-review

95 Citations (Scopus)

Original language	English
Pages (from-to)	15170 - 15175
Number of pages	6
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	99
Issue number	23
DOIs	https://doi.org/10.1073/pnas.212320199
Publication status	Published - 2002

Access to Document

10.1073/pnas.212320199

Cite this

Bowser, D. N., Wagner, D. A., Czajkowski, C., Cromer, B. A., Parker, M. W., Wallace, R. H., Harkin, L. A., Mulley, J. C., Marini, C., Berkovic, S. F., Williams, D. A., Jones, M. V., & Petrou, S. (2002). Altered kinetics and benzodiazepine sensitivity of a GABAA receptor subunit mutation [2(R43Q)] found in human epilepsy. Proceedings of the National Academy of Sciences of the United States of America, 99(23), 15170 - 15175. https://doi.org/10.1073/pnas.212320199

@article{cc47c491eac5401e81233c0fbb331a74,

title = "Altered kinetics and benzodiazepine sensitivity of a GABAA receptor subunit mutation [2(R43Q)] found in human epilepsy",

author = "Bowser, \{David N\} and Wagner, \{David A\} and Cynthia Czajkowski and Cromer, \{Brett A\} and Parker, \{Michael W\} and Wallace, \{Robyn H\} and Harkin, \{Louise A\} and Mulley, \{John C\} and Carla Marini and Berkovic, \{Samuel F\} and Williams, \{David A\} and Jones, \{Mathew V\} and Steven Petrou",

year = "2002",

doi = "10.1073/pnas.212320199",

language = "English",

volume = "99",

pages = "15170 -- 15175",

journal = "Proceedings of the National Academy of Sciences of the United States of America",

issn = "0027-8424",

publisher = "National Academy of Sciences",

number = "23",

}

Bowser, DN, Wagner, DA, Czajkowski, C, Cromer, BA, Parker, MW, Wallace, RH, Harkin, LA, Mulley, JC, Marini, C, Berkovic, SF, Williams, DA, Jones, MV & Petrou, S 2002, 'Altered kinetics and benzodiazepine sensitivity of a GABAA receptor subunit mutation [2(R43Q)] found in human epilepsy', Proceedings of the National Academy of Sciences of the United States of America, vol. 99, no. 23, pp. 15170 - 15175. https://doi.org/10.1073/pnas.212320199

Altered kinetics and benzodiazepine sensitivity of a GABAA receptor subunit mutation [2(R43Q)] found in human epilepsy. / Bowser, David N; Wagner, David A; Czajkowski, Cynthia et al.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, No. 23, 2002, p. 15170 - 15175.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Altered kinetics and benzodiazepine sensitivity of a GABAA receptor subunit mutation [2(R43Q)] found in human epilepsy

AU - Bowser, David N

AU - Wagner, David A

AU - Czajkowski, Cynthia

AU - Cromer, Brett A

AU - Parker, Michael W

AU - Wallace, Robyn H

AU - Harkin, Louise A

AU - Mulley, John C

AU - Marini, Carla

AU - Berkovic, Samuel F

AU - Williams, David A

AU - Jones, Mathew V

AU - Petrou, Steven

PY - 2002

Y1 - 2002

U2 - 10.1073/pnas.212320199

DO - 10.1073/pnas.212320199

M3 - Article

SN - 0027-8424

VL - 99

SP - 15170

EP - 15175

JO - Proceedings of the National Academy of Sciences of the United States of America

JF - Proceedings of the National Academy of Sciences of the United States of America

IS - 23

ER -