Altered hippocampal muscarinic M4, but not M1, receptor expression from subjects with schizophrenia

Elizabeth Scarr, Suresh Sundram, Dahlia Keriakous, Brian Dean

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Abstract

Having shown a decrease in [3H]pirenzepine binding in the hippocampus from subjects with schizophrenia, we wished to determine whether such a change in radioligand binding was associated with changes in hippocampal mRNA for the muscarinic1 (M1) and muscarinic4 (M4) receptors in tissue from different cohorts of subjects
Original languageEnglish
Pages (from-to)1161 - 1170
Number of pages10
JournalBiological Psychiatry
Volume61
Issue number10
Publication statusPublished - 2007

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