Allosteric modulation of the calcium-sensing receptor by gamma-glutamyl peptides inhibition of PTH secretion, suppression of intraceullar cAMP levels and a common mechanism of action with L-amino acids

Geoffrey Broadhead; Hee-chang Mun; Vimesh Avlani; Orane Jourdon; W Church; Arthur Christopoulos; Leigh Delbridge; Arthur Conigrave

Allosteric modulation of the calcium-sensing receptor by gamma-glutamyl peptides inhibition of PTH secretion, suppression of intraceullar cAMP levels and a common mechanism of action with L-amino acids

Geoffrey Broadhead, Hee-chang Mun, Vimesh Avlani, Orane Jourdon, W Church, Arthur Christopoulos, Leigh Delbridge, Arthur Conigrave

Research output: Contribution to journal › Article › Research › peer-review

75 Citations (Scopus)

Original language	English
Pages (from-to)	8786 - 8797
Number of pages	12
Journal	Journal of Biological Chemistry
Volume	286
Issue number	11
Publication status	Published - 2011

Cite this

Broadhead, G., Mun, H., Avlani, V., Jourdon, O., Church, W., Christopoulos, A., Delbridge, L., & Conigrave, A. (2011). Allosteric modulation of the calcium-sensing receptor by gamma-glutamyl peptides inhibition of PTH secretion, suppression of intraceullar cAMP levels and a common mechanism of action with L-amino acids. Journal of Biological Chemistry, 286(11), 8786 - 8797.

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title = "Allosteric modulation of the calcium-sensing receptor by gamma-glutamyl peptides inhibition of PTH secretion, suppression of intraceullar cAMP levels and a common mechanism of action with L-amino acids",

author = "Geoffrey Broadhead and Hee-chang Mun and Vimesh Avlani and Orane Jourdon and W Church and Arthur Christopoulos and Leigh Delbridge and Arthur Conigrave",

year = "2011",

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volume = "286",

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Broadhead, G, Mun, H, Avlani, V, Jourdon, O, Church, W, Christopoulos, A, Delbridge, L & Conigrave, A 2011, 'Allosteric modulation of the calcium-sensing receptor by gamma-glutamyl peptides inhibition of PTH secretion, suppression of intraceullar cAMP levels and a common mechanism of action with L-amino acids', Journal of Biological Chemistry, vol. 286, no. 11, pp. 8786 - 8797.

Allosteric modulation of the calcium-sensing receptor by gamma-glutamyl peptides inhibition of PTH secretion, suppression of intraceullar cAMP levels and a common mechanism of action with L-amino acids. / Broadhead, Geoffrey; Mun, Hee-chang; Avlani, Vimesh et al.

In: Journal of Biological Chemistry, Vol. 286, No. 11, 2011, p. 8786 - 8797.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Allosteric modulation of the calcium-sensing receptor by gamma-glutamyl peptides inhibition of PTH secretion, suppression of intraceullar cAMP levels and a common mechanism of action with L-amino acids

AU - Broadhead, Geoffrey

AU - Mun, Hee-chang

AU - Avlani, Vimesh

AU - Jourdon, Orane

AU - Church, W

AU - Christopoulos, Arthur

AU - Delbridge, Leigh

AU - Conigrave, Arthur

PY - 2011

Y1 - 2011

M3 - Article

VL - 286

SP - 8786

EP - 8797

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

SN - 1083-351X

IS - 11

ER -