Allosteric modulation of seven transmembrane spanning receptors: theory, practice, and opportunities for central nervous system drug discovery

Bruce J Melancon, Corey R Hopkins, Michael R Wood, Kyle A Emmitte, Colleen M Niswender, Arthur Christopoulos, Peter Jeffrey Conn, Craig W Lindsley

Research output: Contribution to journalArticleResearchpeer-review

Original languageEnglish
Pages (from-to)1445 - 1464
Number of pages20
JournalJournal of Medicinal Chemistry
Volume55
Issue number4
DOIs
Publication statusPublished - 2012

Cite this

Melancon, Bruce J ; Hopkins, Corey R ; Wood, Michael R ; Emmitte, Kyle A ; Niswender, Colleen M ; Christopoulos, Arthur ; Conn, Peter Jeffrey ; Lindsley, Craig W. / Allosteric modulation of seven transmembrane spanning receptors: theory, practice, and opportunities for central nervous system drug discovery. In: Journal of Medicinal Chemistry. 2012 ; Vol. 55, No. 4. pp. 1445 - 1464.
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title = "Allosteric modulation of seven transmembrane spanning receptors: theory, practice, and opportunities for central nervous system drug discovery",
author = "Melancon, {Bruce J} and Hopkins, {Corey R} and Wood, {Michael R} and Emmitte, {Kyle A} and Niswender, {Colleen M} and Arthur Christopoulos and Conn, {Peter Jeffrey} and Lindsley, {Craig W}",
year = "2012",
doi = "10.1021/jm201139r",
language = "English",
volume = "55",
pages = "1445 -- 1464",
journal = "Journal of Medicinal Chemistry",
issn = "0022-2623",
publisher = "AMER CHEMICAL SOC",
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}

Allosteric modulation of seven transmembrane spanning receptors: theory, practice, and opportunities for central nervous system drug discovery. / Melancon, Bruce J; Hopkins, Corey R; Wood, Michael R; Emmitte, Kyle A; Niswender, Colleen M; Christopoulos, Arthur; Conn, Peter Jeffrey; Lindsley, Craig W.

In: Journal of Medicinal Chemistry, Vol. 55, No. 4, 2012, p. 1445 - 1464.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Allosteric modulation of seven transmembrane spanning receptors: theory, practice, and opportunities for central nervous system drug discovery

AU - Melancon, Bruce J

AU - Hopkins, Corey R

AU - Wood, Michael R

AU - Emmitte, Kyle A

AU - Niswender, Colleen M

AU - Christopoulos, Arthur

AU - Conn, Peter Jeffrey

AU - Lindsley, Craig W

PY - 2012

Y1 - 2012

UR - http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349997/pdf/nihms345458.pdf

U2 - 10.1021/jm201139r

DO - 10.1021/jm201139r

M3 - Article

VL - 55

SP - 1445

EP - 1464

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

SN - 0022-2623

IS - 4

ER -