Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: Implications for drug screening

Cassandra Koole, Denise Wootten, John Simms, Celine Valant, Rohan Sridhar, Owen Woodman, Laurence J Miller, Roger Summers, Arthur Christopoulos, Patrick M Sexton

Research output: Contribution to journalArticleResearchpeer-review

Original languageEnglish
Pages (from-to)456 - 465
Number of pages10
JournalMolecular Pharmacology
Volume78
Issue number3
DOIs
Publication statusPublished - 2010

Cite this

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title = "Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: Implications for drug screening",
author = "Cassandra Koole and Denise Wootten and John Simms and Celine Valant and Rohan Sridhar and Owen Woodman and Miller, {Laurence J} and Roger Summers and Arthur Christopoulos and Sexton, {Patrick M}",
year = "2010",
doi = "10.1124/mol.110.065664",
language = "English",
volume = "78",
pages = "456 -- 465",
journal = "Molecular Pharmacology",
issn = "1521-0111",
publisher = "ACS Books",
number = "3",

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TY - JOUR

T1 - Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: Implications for drug screening

AU - Koole, Cassandra

AU - Wootten, Denise

AU - Simms, John

AU - Valant, Celine

AU - Sridhar, Rohan

AU - Woodman, Owen

AU - Miller, Laurence J

AU - Summers, Roger

AU - Christopoulos, Arthur

AU - Sexton, Patrick M

PY - 2010

Y1 - 2010

UR - http://molpharm.aspetjournals.org/content/78/3/456.full.pdf+html

U2 - 10.1124/mol.110.065664

DO - 10.1124/mol.110.065664

M3 - Article

VL - 78

SP - 456

EP - 465

JO - Molecular Pharmacology

JF - Molecular Pharmacology

SN - 1521-0111

IS - 3

ER -