Abstract
To achieve and maintain fertility, the adult mammalian testis produces many generations of sperm. While testicular integrity is
established in the fetus and develops further in juvenile life, sperm production does not ensue until much later in life, following
the onset of puberty. Signals from the transforming growth factor-b superfamily of proteins are vital for governance of testis
development and spermatogenesis, and this review discusses our current understanding of the mechanisms and processes in
which they have been implicated with a focus on the fetal and juvenile testis
| Original language | English |
|---|---|
| Pages (from-to) | 233 - 246 |
| Number of pages | 14 |
| Journal | Reproduction |
| Volume | 132 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 2006 |