AlCl3 mediated unexpected migration of sulfonyl groups: regioselective synthesis of 7-sulfonyl indoles of potential pharmacological interest

Bagineni Prasad, Raju Adepu, Sandhya Sandra, D. Rambabu, G. Rama Krishna, C. Malla Reddy, Girdhar Singh Deora, Parimal Misra, Manojit Pal

Research output: Contribution to journalArticleResearchpeer-review

44 Citations (Scopus)

Abstract

A conceptually new and straightforward introduction of sulfonyl groups at the C-7 position of an indole ring has been achieved via AlCl 3 mediated unexpected regioselective sulfonyl group migration for N-alkyl/aryl/heteroarylsulfonyl indoles affording potential inhibitors of Mycobacterium tuberculosis H37Rv chorismate mutase. 

Original languageEnglish
Pages (from-to)10434-10436
Number of pages3
JournalChemical Communications
Volume48
Issue number84
DOIs
Publication statusPublished - 28 Oct 2012
Externally publishedYes

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