Agreement between pharmaceutical claims data and patient-reported medication use after stroke

Lachlan L. Dalli, Nadine E. Andrew, Dominique A. Cadilhac, Joosup Kim, Frank M. Sanfilippo, Monique F. Kilkenny, on behalf of the PRECISE investigators

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OBJECTIVES: To assess the agreement between pharmaceutical claims data and patient-reported medication use after stroke. METHODS: Claims data from the Pharmaceutical Benefits Scheme were used to estimate medication use for a subset of participants registered in the Australian Stroke Clinical Registry in 2016. Estimates on medication use were validated against patient-reported responses (considered the reference standard). KEY FINDINGS: For antihypertensive and lipid-lowering medications, the sensitivity of claims data was excellent (85-87%) and the specificity was good (73-78%). Whereas for antithrombotic medications, sensitivity was modest (61%), but specificity was excellent (85%). CONCLUSIONS: Pharmaceutical claims data can be used to infer medication use after stroke with mostly good to excellent sensitivity and specificity compared with the patient report.

Original languageEnglish
Pages (from-to)397-399
Number of pages3
JournalInternational Journal of Pharmacy Practice
Issue number4
Publication statusPublished - Aug 2021


  • administrative claims
  • healthcare validation study
  • pharmacoepidemiology
  • registries
  • stroke

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