Age-associated changes in monocyte and innate immune activation markers occur more rapidly in HIV infected women

Genevieve Martin; Maelenn Gouillou; Anna Clare Hearps; Thomas A Angelovich; Allen Cheuk-Seng Cheng; Fiona Lynch; Wan-Jung Cheng; Geza Paukovics; Clovis Prince-Steve Palmer; Richard M Novak; Anthony Jaworowski; Alan L Landay; Suzanne Mary Crowe

doi:10.1371/journal.pone.0055279

Age-associated changes in monocyte and innate immune activation markers occur more rapidly in HIV infected women

Genevieve Martin, Maelenn Gouillou, Anna Clare Hearps, Thomas A Angelovich, Allen Cheuk-Seng Cheng, Fiona Lynch, Wan-Jung Cheng, Geza Paukovics, Clovis Prince-Steve Palmer, Richard M Novak, Anthony Jaworowski, Alan L Landay, Suzanne Mary Crowe

Medicine Alfred Hospital

Research output: Contribution to journal › Article › Research › peer-review

96 Citations (Scopus)

Abstract

Quantifying the impact of HIV on immune aging reveals that HIV infection in women confers the equivalent of a 10-14 year increase in the levels of innate immune aging markers. These changes may contribute to the increased risk of inflammatory age-related diseases in HIV positive women.

Original language	English
Article number	e55279
Number of pages	7
Journal	PLoS ONE
Volume	8
Issue number	1
DOIs	https://doi.org/10.1371/journal.pone.0055279
Publication status	Published - 2013

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10.1371/journal.pone.0055279Licence: CC BY

Cite this

Martin, G., Gouillou, M., Hearps, A. C., Angelovich, T. A., Cheng, A. C.-S., Lynch, F., Cheng, W.-J., Paukovics, G., Palmer, C. P.-S., Novak, R. M., Jaworowski, A., Landay, A. L., & Crowe, S. M. (2013). Age-associated changes in monocyte and innate immune activation markers occur more rapidly in HIV infected women. PLoS ONE, 8(1), Article e55279. https://doi.org/10.1371/journal.pone.0055279

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abstract = "Quantifying the impact of HIV on immune aging reveals that HIV infection in women confers the equivalent of a 10-14 year increase in the levels of innate immune aging markers. These changes may contribute to the increased risk of inflammatory age-related diseases in HIV positive women.",

author = "Genevieve Martin and Maelenn Gouillou and Hearps, {Anna Clare} and Angelovich, {Thomas A} and Cheng, {Allen Cheuk-Seng} and Fiona Lynch and Wan-Jung Cheng and Geza Paukovics and Palmer, {Clovis Prince-Steve} and Novak, {Richard M} and Anthony Jaworowski and Landay, {Alan L} and Crowe, {Suzanne Mary}",

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AU - Cheng, Allen Cheuk-Seng

AU - Lynch, Fiona

AU - Cheng, Wan-Jung

AU - Paukovics, Geza

AU - Palmer, Clovis Prince-Steve

AU - Novak, Richard M

AU - Jaworowski, Anthony

AU - Landay, Alan L

AU - Crowe, Suzanne Mary

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Age-associated changes in monocyte and innate immune activation markers occur more rapidly in HIV infected women

Abstract

UN SDGs

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Improving the prevention and clinical management of infectious diseases

Cite this

Age-associated changes in monocyte and innate immune activation markers occur more rapidly in HIV infected women

Abstract

UN SDGs

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Improving the prevention and clinical management of infectious diseases

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