Affective trajectories before and after a quit attempt among smokers with current depressive disorders

Amanda R B Mathew, Jason D B Robinson, Peter Joseph Norton, Paul M B Cinciripini, Richard A B Brown, Janice A B Blalock

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)


Background: Smoking cessation for individuals with depressive disorders represents an important clinical issue. It often has been hypothesized that smoking cessation worsens negative affect as part of the withdrawal process in this population. However, studies examining the impact of smoking cessation on changes in affect in smokers with depression are limited and equivocal. Methods: This study examines affective processes in smokers with depression undergoing a 12-week smoking cessation intervention (N = 49). We used the Positive and Negative Affect Scale to measure participants positive affect (PA) and negative affect (NA) trajectories over the course of a quit attempt. We examined whether affective treatment response across the trial differed by prolonged smoking abstinence status and whether postquit affect differed by prequit affective treatment response, as well as the interaction of prequit affective response and abstinence status. Results: Prolonged abstainers showed significant increases in PA over the course of a quit attempt compared with nonabstainers. Prequit affective trajectories significantly predicted postquit affect for measures of both PA and NA. Lastly, the interaction of prequit affective trajectory and abstinence significantly predicted postquit levels of NA but not PA. Conclusions: This study adds to a burgeoning body of research demonstrating that significant improvements in psychological functioning can be observed among those who successfully quit smoking even in the most severe psychiatric group
Original languageEnglish
Pages (from-to)1807 - 1815
Number of pages9
JournalNicotine and Tobacco Research
Issue number11
Publication statusPublished - 2013
Externally publishedYes

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