Adverse effects in epilepsy: Recognition, measurement, and taxonomy

Frank G. Gilliam, Laura S. Snavely, Piero Perucca

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

1 Citation (Scopus)

Abstract

The goal of balancing adverse the side effects of a medication with its efficacy for seizures has been a primary topic in the epilepsy community since the discussion of bromide therapy by Sieveking and Locock at a meeting of the Royal Medical Society in London in 1857. The conventional means of identifying adverse medication effects has been direct questioning of the patient in the clinic setting. Several instruments have been developed to assess seizure medication adverse effects in a reliable and valid manner. Medication side effects have typically been presented in clinical studies as lists of symptoms or medical problems. The combination of medication side effects and comorbid mood disorders explains the large majority of variance in quality of life (QOL) and thus it is pertinent for the treating clinician to accurately assess and effectively address the patient's medication burden in order to maximize QOL.
Original languageEnglish
Title of host publicationEpilepsy and the Interictal State
Subtitle of host publicationCo-morbidities and Quality of Life
EditorsErik K. St. Louis, David M. Ficker, Terence J. O’Brien
Place of PublicationUnited State
PublisherJohn Wiley & Sons
Chapter8
Pages102-109
Number of pages8
ISBN (Electronic)9781118951026
ISBN (Print)9780470656235
DOIs
Publication statusPublished - 3 Aug 2015
Externally publishedYes

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