Advances of Melatonin-Based Therapies in the Treatment of Disturbed Sleep and Mood

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6 Citations (Scopus)


Melatonin and melatonin agonists offer novel treatments for sleep and mood disorders, particularly where circadian misalignment is also present. The therapies offer both phase-shifting and sleep-promoting effects and have shown potential to treat advanced and delayed sleep-wake phase disorder, non-24-h sleep-wake cycle, jetlag, shift work disorder, insomnia, seasonal affective disorder and major depressive disorder.

Original languageEnglish
Title of host publicationHandbook of Experimental Pharmacology
EditorsHans-Peter Landolt, Derk-Jan Dijk
Place of PublicationCham, Switzerland
Number of pages15
ISBN (Electronic)9783030112721
ISBN (Print)9783030112707
Publication statusPublished - 2019

Publication series

NameHandbook of Experimental Pharmacology
ISSN (Print)0171-2004
ISSN (Electronic)1865-0325


  • Agomelatine
  • Circadian rhythm
  • Circadin
  • Major depressive disorder
  • Melatonin
  • Melatonin agonist
  • Mood
  • Ramelteon
  • Sleep
  • Tasimelteon

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