Advances in Porous Silicon–Based Nanomaterials for Diagnostic and Therapeutic Applications

Research output: Contribution to journalReview ArticleResearchpeer-review

Abstract

This review provides a perspective on porous silicon (pSi)–based nanomaterials including nanoparticles, nanowires, and thin films, that are currently being used in advanced therapy, imaging, and sensing, with a focus on their effective use in future clinical settings. The achievement of both controlled geometry and architecture, and surface chemistry motifs, are presented as the two key parameters that dictate the nature of interactions with the biological entities. The authors discuss the role of the degradation kinetics in a biological environment into nontoxic by‐products. pSi is presented as increasingly fulfilling a central task in various biomedical applications and clinical settings, owing to its unique physiochemical properties.
Original languageEnglish
Article number1800095
Number of pages25
JournalAdvanced Therapeutics
Volume2
Issue number1
DOIs
Publication statusPublished - Jan 2019

Keywords

  • Biosensors
  • Diagnosis
  • Drug delivery
  • Nanomedicine
  • Porous silicon

Cite this

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title = "Advances in Porous Silicon–Based Nanomaterials for Diagnostic and Therapeutic Applications",
abstract = "This review provides a perspective on porous silicon (pSi)–based nanomaterials including nanoparticles, nanowires, and thin films, that are currently being used in advanced therapy, imaging, and sensing, with a focus on their effective use in future clinical settings. The achievement of both controlled geometry and architecture, and surface chemistry motifs, are presented as the two key parameters that dictate the nature of interactions with the biological entities. The authors discuss the role of the degradation kinetics in a biological environment into nontoxic by‐products. pSi is presented as increasingly fulfilling a central task in various biomedical applications and clinical settings, owing to its unique physiochemical properties.",
keywords = "Biosensors, Diagnosis, Drug delivery, Nanomedicine, Porous silicon",
author = "Terence Tieu and {Alba Martin}, Maria and Roey Elnathan and Anna Cifuentes-Rius and Voelcker, {Nicolas Hans}",
year = "2019",
month = "1",
doi = "10.1002/adtp.201800095",
language = "English",
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journal = "Advanced Therapeutics",
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Advances in Porous Silicon–Based Nanomaterials for Diagnostic and Therapeutic Applications. / Tieu, Terence; Alba Martin, Maria; Elnathan, Roey; Cifuentes-Rius, Anna; Voelcker, Nicolas Hans.

In: Advanced Therapeutics, Vol. 2, No. 1, 1800095, 01.2019.

Research output: Contribution to journalReview ArticleResearchpeer-review

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AU - Tieu, Terence

AU - Alba Martin, Maria

AU - Elnathan, Roey

AU - Cifuentes-Rius, Anna

AU - Voelcker, Nicolas Hans

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KW - Biosensors

KW - Diagnosis

KW - Drug delivery

KW - Nanomedicine

KW - Porous silicon

U2 - 10.1002/adtp.201800095

DO - 10.1002/adtp.201800095

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