Advances and future directions for management of trauma patients with musculoskeletal injuries

Zsolt Balogh, Marie K Reumann, Russell Lindsay Gruen, Philipp Mayer-Kuckuk, Michael A Schuetz, Ian A Harris, Belinda Jane Gabbe, Mohit Bhandari

Research output: Contribution to journalArticleResearchpeer-review

84 Citations (Scopus)


Musculoskeletal injuries are the most common reason for operative procedures in severely injured patients and are major determinants of functional outcomes. In this paper, we summarise advances and future directions for management of multiply injured patients with major musculoskeletal trauma. Improved understanding of fracture healing has created new possibilities for management of particularly challenging problems, such as delayed union and non union of fractures and large bone defects. Optimum timing of major orthopaedic interventions is guided by increased knowledge about the immune response after injury. Individual treatment should be guided by trading off the benefits of early definitive skeletal stabilisation, and the potentially life-threatening risks of systemic complications such as fat embolism, acute lung injury, and multiple organ failure. New methods for measurement of fracture healing and function and quality of life outcomes pave the way for landmark trials that will guide the future management of musculoskeletal injuries
Original languageEnglish
Pages (from-to)1109 - 1119
Number of pages11
JournalThe Lancet
Issue number9847
Publication statusPublished - 2012

Cite this