TY - JOUR
T1 - Advances and future directions for management of trauma patients with musculoskeletal injuries
AU - Balogh, Zsolt
AU - Reumann, Marie K
AU - Gruen, Russell Lindsay
AU - Mayer-Kuckuk, Philipp
AU - Schuetz, Michael A
AU - Harris, Ian A
AU - Gabbe, Belinda Jane
AU - Bhandari, Mohit
PY - 2012
Y1 - 2012
N2 - Musculoskeletal injuries are the most common reason for operative procedures in severely injured patients and are major determinants of functional outcomes. In this paper, we summarise advances and future directions for management of multiply injured patients with major musculoskeletal trauma. Improved understanding of fracture healing has created new possibilities for management of particularly challenging problems, such as delayed union and non union of fractures and large bone defects. Optimum timing of major orthopaedic interventions is guided by increased knowledge about the immune response after injury. Individual treatment should be guided by trading off the benefits of early definitive skeletal stabilisation, and the potentially life-threatening risks of systemic complications such as fat embolism, acute lung injury, and multiple organ failure. New methods for measurement of fracture healing and function and quality of life outcomes pave the way for landmark trials that will guide the future management of musculoskeletal injuries
AB - Musculoskeletal injuries are the most common reason for operative procedures in severely injured patients and are major determinants of functional outcomes. In this paper, we summarise advances and future directions for management of multiply injured patients with major musculoskeletal trauma. Improved understanding of fracture healing has created new possibilities for management of particularly challenging problems, such as delayed union and non union of fractures and large bone defects. Optimum timing of major orthopaedic interventions is guided by increased knowledge about the immune response after injury. Individual treatment should be guided by trading off the benefits of early definitive skeletal stabilisation, and the potentially life-threatening risks of systemic complications such as fat embolism, acute lung injury, and multiple organ failure. New methods for measurement of fracture healing and function and quality of life outcomes pave the way for landmark trials that will guide the future management of musculoskeletal injuries
UR - http://www.sciencedirect.com/science/article/pii/S014067361260991X#
U2 - 10.1016/S0140-6736(12)60991-X
DO - 10.1016/S0140-6736(12)60991-X
M3 - Article
SN - 0140-6736
VL - 380
SP - 1109
EP - 1119
JO - The Lancet
JF - The Lancet
IS - 9847
ER -