Adolescent precursors of cannabis dependence: Findings from the Victorian adolescent health cohort study

Carolyn Coffey, John B. Carlin, Michael Lynskey, Ning Li, George C. Patton

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Background: Dependence increases the likelihood of adverse consequences of cannabis use, but its aetiology is poorly understood. Aims: To examine adolescent precursors of young-adult cannabis dependence. Method: Putative risk factors were measured in a representative sample (n=2032) of secondary students in the State of Victoria, Australia, six times between 1992 and 1995. Cannabis dependence was assessed in 1998, at age 20-21 years. Results: Of 1601 young adults, 115 met criteria for cannabis dependence. Male gender (OR=2.6, P<0.01), regular cannabis use (weekly: OR=4.9; daily: OR=4.6, P=0.02), persistent antisocial behaviour (linear effect P=0.03) and persistent cigarette smoking (linear effect P=0.02) independently predicted cannabis dependence. Neither smoking severity (P=0.83) nor persistent psychiatric morbidity (linear effect P=0.26) independently predicted dependence. Regular cannabis use increased risk only in the absence of persistent problematic alcohol use. Conclusions: Weekly cannabis use marks a threshold for increased risk of later dependence, with selection of cannabis in preference to alcohol possibly indicating an early addiction process.

Original languageEnglish
Pages (from-to)330-336
Number of pages7
JournalBritish Journal of Psychiatry
Issue numberAPR.
Publication statusPublished - 1 Apr 2003
Externally publishedYes

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